Possible Options for New Pertussis Vaccines

Increasing evidence that the currently available acellular pertussis vaccines are not providing optimal control of pertussis in the United States and many other countries has stimulated interest in improvements of the current vaccines and in the development of new vaccines. A better understanding of...

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Veröffentlicht in:The Journal of infectious diseases 2014-04, Vol.209 (suppl 1), p.S24-S27
Hauptverfasser: Meade, Bruce D., Plotkin, Stanley A., Locht, Camille
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container_title The Journal of infectious diseases
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creator Meade, Bruce D.
Plotkin, Stanley A.
Locht, Camille
description Increasing evidence that the currently available acellular pertussis vaccines are not providing optimal control of pertussis in the United States and many other countries has stimulated interest in improvements of the current vaccines and in the development of new vaccines. A better understanding of the limitations of the current vaccines and the basis for the pertussis resurgence is needed to design improved vaccines. This article outlines several alternate approaches and summarizes the challenges related to the development of new or modified vaccines.
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source MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection
subjects Acellular vaccines
Animal models
Antigens
Bacterial vaccines
Combined vaccines
Communicable Diseases, Emerging - epidemiology
Communicable Diseases, Emerging - prevention & control
Diptheria pertussis tetanus vaccines
Humans
Pertussis Vaccine - immunology
Pertussis Vaccine - isolation & purification
Toxoid vaccines
United States - epidemiology
Vaccination
Vaccines, Acellular - immunology
Vaccines, Acellular - isolation & purification
Viral vaccines
Whooping cough
Whooping Cough - epidemiology
Whooping Cough - prevention & control
title Possible Options for New Pertussis Vaccines
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