Possible Options for New Pertussis Vaccines
Increasing evidence that the currently available acellular pertussis vaccines are not providing optimal control of pertussis in the United States and many other countries has stimulated interest in improvements of the current vaccines and in the development of new vaccines. A better understanding of...
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Veröffentlicht in: | The Journal of infectious diseases 2014-04, Vol.209 (suppl 1), p.S24-S27 |
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container_title | The Journal of infectious diseases |
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creator | Meade, Bruce D. Plotkin, Stanley A. Locht, Camille |
description | Increasing evidence that the currently available acellular pertussis vaccines are not providing optimal control of pertussis in the United States and many other countries has stimulated interest in improvements of the current vaccines and in the development of new vaccines. A better understanding of the limitations of the current vaccines and the basis for the pertussis resurgence is needed to design improved vaccines. This article outlines several alternate approaches and summarizes the challenges related to the development of new or modified vaccines. |
doi_str_mv | 10.1093/infdis/jit531 |
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source | MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
subjects | Acellular vaccines Animal models Antigens Bacterial vaccines Combined vaccines Communicable Diseases, Emerging - epidemiology Communicable Diseases, Emerging - prevention & control Diptheria pertussis tetanus vaccines Humans Pertussis Vaccine - immunology Pertussis Vaccine - isolation & purification Toxoid vaccines United States - epidemiology Vaccination Vaccines, Acellular - immunology Vaccines, Acellular - isolation & purification Viral vaccines Whooping cough Whooping Cough - epidemiology Whooping Cough - prevention & control |
title | Possible Options for New Pertussis Vaccines |
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