GM2 Gangliosidosis in British Jacob Sheep

GM2 gangliosidosis (Tay–Sachs disease) was diagnosed in 6- to 8-month-old pedigree Jacob lambs from two unrelated flocks presenting clinically with progressive neurological dysfunction of 10 day's to 8 week's duration. Clinical signs included hindlimb ataxia and weakness, recumbency and pr...

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Veröffentlicht in:	Journal of comparative pathology 2014-02, Vol.150 (2-3), p.253-257
Hauptverfasser:	Wessels, M.E., Holmes, J.P., Jeffrey, M., Jackson, M., Mackintosh, A., Kolodny, E.H., Zeng, B.J., Wang, C.B., Scholes, S.F.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta-Hexosaminidase alpha Chain - genetics Gangliosidoses, GM2 - genetics Gangliosidoses, GM2 - pathology Gangliosidoses, GM2 - veterinary GM2 gangliosidosis Jacob sheep Mutation Sheep Sheep Diseases - genetics Sheep Diseases - pathology Tay–Sachs disease
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