Human malaria in C57BL/6J mice: an in vivo model for chemotherapy studies

The present work deals with the development of Plasmodium falciparum stages in mouse model and its potential for the study of efficacy of antimalarial drugs. C57BL/6J mice were infected with multidrug resistant P. falciparum strain then treated with arteether and artesunate. A response was observed...

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Veröffentlicht in:	Indian journal of experimental biology 2014-01, Vol.52 (1), p.67-72
Hauptverfasser:	Sunita, K, Rajyalakshmi, M, Kumar, K Kalyan, Sowjanya, M, Satish, P V V, Prasad, D Madhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Artemisinins - administration & dosage Disease Models, Animal Drug Resistance, Multiple - genetics Female Humans Malaria - drug therapy Malaria - metabolism Malaria - parasitology Mice Mice, Inbred C57BL Parasitemia - drug therapy Plasmodium falciparum - growth & development Plasmodium falciparum - pathogenicity
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