Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases
This study was designed to estimate interferon-gamma (INF-gamma) levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus (HBV and HCV) status...
Gespeichert in:
| Veröffentlicht in: | Eastern Mediterranean health journal 2013-05, Vol.19 (5), p.490-494 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 494 |
|---|---|
| container_issue | 5 |
| container_start_page | 490 |
| container_title | Eastern Mediterranean health journal |
| container_volume | 19 |
| creator | Roshdy, M N Harfoush, R A Hamed, N A Morsi, M G |
| description | This study was designed to estimate interferon-gamma (INF-gamma) levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus (HBV and HCV) status were conducted on 20 unsplenectomized patients with gamma-thalassaemia major and 20 patients with acute myeloid leukaemia (AML) in the maintenance phase and 20 healthy subjects. Mean haemoglobin levels and red blood cell counts were significantly higher in the control group than the AML and thalassaemia groups, while white blood cell counts were significantly lower in the control group than the case groups. Two AML patients (10%) and 1 thalassaemia patient (5%) were HBV-positive, while 5% of both case groups were HCV-positive. Mean values of INF-gamma were significantly different between AML, thalassaemia major and control groups: 5517 (SD 1142) pg/mL, 1024 (SD 249) pg/mL and 2980 (SD 604) pg/mL respectively. |
| doi_str_mv | 10.26719/2013.19.5.490 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1507187944</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1507187944</sourcerecordid><originalsourceid>FETCH-LOGICAL-c335t-92e972b454f061589cde25b3fda9140549bf7ff1544b5474c052cf831cfde0fa3</originalsourceid><addsrcrecordid>eNo9kE1LxDAYhIMo7rp69Sg5emnNZ9McZVk_YEEEPZe0fVMrbbM26UL_vdFdPc0cZgbmQeiakpRliuo7RihPqU5lKjQ5QUua5SqhGRen0RNGEs61WqAL7z8JYXku2DlaMJFRRTlZovJ1MkNogwntHjD40PbRugE7i9shwGhhdEPSmL43uIM9dB6b3g0N3jTzLrRmwDvXzWE0g7eThxp_GIgTrnPNjCvjwV-iM2s6D1dHXaH3h83b-inZvjw-r--3ScW5DIlmoBUrhRSWZFTmuqqByZLb2mgqiBS6tMpaKoUopVCiIpJVNue0sjUQa_gK3R52d6P7muKVom99BV1nBnCTL6gkiuZKCxGj6SFajc77EWyxG-PxcS4oKX65Fj9ci6iyiFxj4ea4PZU91P_xP5D8G5T5dNE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1507187944</pqid></control><display><type>article</type><title>Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Roshdy, M N ; Harfoush, R A ; Hamed, N A ; Morsi, M G</creator><creatorcontrib>Roshdy, M N ; Harfoush, R A ; Hamed, N A ; Morsi, M G</creatorcontrib><description>This study was designed to estimate interferon-gamma (INF-gamma) levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus (HBV and HCV) status were conducted on 20 unsplenectomized patients with gamma-thalassaemia major and 20 patients with acute myeloid leukaemia (AML) in the maintenance phase and 20 healthy subjects. Mean haemoglobin levels and red blood cell counts were significantly higher in the control group than the AML and thalassaemia groups, while white blood cell counts were significantly lower in the control group than the case groups. Two AML patients (10%) and 1 thalassaemia patient (5%) were HBV-positive, while 5% of both case groups were HCV-positive. Mean values of INF-gamma were significantly different between AML, thalassaemia major and control groups: 5517 (SD 1142) pg/mL, 1024 (SD 249) pg/mL and 2980 (SD 604) pg/mL respectively.</description><identifier>ISSN: 1020-3397</identifier><identifier>EISSN: 1687-1634</identifier><identifier>DOI: 10.26719/2013.19.5.490</identifier><identifier>PMID: 24617130</identifier><language>eng</language><publisher>Egypt</publisher><subject>beta-Thalassemia - blood ; beta-Thalassemia - therapy ; Blood Transfusion - statistics & numerical data ; Blood Transfusion - utilization ; Case-Control Studies ; Egypt ; Erythrocyte Count ; Hemoglobins - analysis ; Hepacivirus - isolation & purification ; Hepatitis B virus - isolation & purification ; Humans ; Interferon-gamma - blood ; Leukemia, Myeloid, Acute - blood ; Leukemia, Myeloid, Acute - therapy ; Leukocyte Count ; Transfusion Reaction</subject><ispartof>Eastern Mediterranean health journal, 2013-05, Vol.19 (5), p.490-494</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-92e972b454f061589cde25b3fda9140549bf7ff1544b5474c052cf831cfde0fa3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24617130$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Roshdy, M N</creatorcontrib><creatorcontrib>Harfoush, R A</creatorcontrib><creatorcontrib>Hamed, N A</creatorcontrib><creatorcontrib>Morsi, M G</creatorcontrib><title>Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases</title><title>Eastern Mediterranean health journal</title><addtitle>East Mediterr Health J</addtitle><description>This study was designed to estimate interferon-gamma (INF-gamma) levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus (HBV and HCV) status were conducted on 20 unsplenectomized patients with gamma-thalassaemia major and 20 patients with acute myeloid leukaemia (AML) in the maintenance phase and 20 healthy subjects. Mean haemoglobin levels and red blood cell counts were significantly higher in the control group than the AML and thalassaemia groups, while white blood cell counts were significantly lower in the control group than the case groups. Two AML patients (10%) and 1 thalassaemia patient (5%) were HBV-positive, while 5% of both case groups were HCV-positive. Mean values of INF-gamma were significantly different between AML, thalassaemia major and control groups: 5517 (SD 1142) pg/mL, 1024 (SD 249) pg/mL and 2980 (SD 604) pg/mL respectively.</description><subject>beta-Thalassemia - blood</subject><subject>beta-Thalassemia - therapy</subject><subject>Blood Transfusion - statistics & numerical data</subject><subject>Blood Transfusion - utilization</subject><subject>Case-Control Studies</subject><subject>Egypt</subject><subject>Erythrocyte Count</subject><subject>Hemoglobins - analysis</subject><subject>Hepacivirus - isolation & purification</subject><subject>Hepatitis B virus - isolation & purification</subject><subject>Humans</subject><subject>Interferon-gamma - blood</subject><subject>Leukemia, Myeloid, Acute - blood</subject><subject>Leukemia, Myeloid, Acute - therapy</subject><subject>Leukocyte Count</subject><subject>Transfusion Reaction</subject><issn>1020-3397</issn><issn>1687-1634</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1LxDAYhIMo7rp69Sg5emnNZ9McZVk_YEEEPZe0fVMrbbM26UL_vdFdPc0cZgbmQeiakpRliuo7RihPqU5lKjQ5QUua5SqhGRen0RNGEs61WqAL7z8JYXku2DlaMJFRRTlZovJ1MkNogwntHjD40PbRugE7i9shwGhhdEPSmL43uIM9dB6b3g0N3jTzLrRmwDvXzWE0g7eThxp_GIgTrnPNjCvjwV-iM2s6D1dHXaH3h83b-inZvjw-r--3ScW5DIlmoBUrhRSWZFTmuqqByZLb2mgqiBS6tMpaKoUopVCiIpJVNue0sjUQa_gK3R52d6P7muKVom99BV1nBnCTL6gkiuZKCxGj6SFajc77EWyxG-PxcS4oKX65Fj9ci6iyiFxj4ea4PZU91P_xP5D8G5T5dNE</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>Roshdy, M N</creator><creator>Harfoush, R A</creator><creator>Hamed, N A</creator><creator>Morsi, M G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130501</creationdate><title>Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases</title><author>Roshdy, M N ; Harfoush, R A ; Hamed, N A ; Morsi, M G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-92e972b454f061589cde25b3fda9140549bf7ff1544b5474c052cf831cfde0fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>beta-Thalassemia - blood</topic><topic>beta-Thalassemia - therapy</topic><topic>Blood Transfusion - statistics & numerical data</topic><topic>Blood Transfusion - utilization</topic><topic>Case-Control Studies</topic><topic>Egypt</topic><topic>Erythrocyte Count</topic><topic>Hemoglobins - analysis</topic><topic>Hepacivirus - isolation & purification</topic><topic>Hepatitis B virus - isolation & purification</topic><topic>Humans</topic><topic>Interferon-gamma - blood</topic><topic>Leukemia, Myeloid, Acute - blood</topic><topic>Leukemia, Myeloid, Acute - therapy</topic><topic>Leukocyte Count</topic><topic>Transfusion Reaction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roshdy, M N</creatorcontrib><creatorcontrib>Harfoush, R A</creatorcontrib><creatorcontrib>Hamed, N A</creatorcontrib><creatorcontrib>Morsi, M G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Eastern Mediterranean health journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roshdy, M N</au><au>Harfoush, R A</au><au>Hamed, N A</au><au>Morsi, M G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases</atitle><jtitle>Eastern Mediterranean health journal</jtitle><addtitle>East Mediterr Health J</addtitle><date>2013-05-01</date><risdate>2013</risdate><volume>19</volume><issue>5</issue><spage>490</spage><epage>494</epage><pages>490-494</pages><issn>1020-3397</issn><eissn>1687-1634</eissn><abstract>This study was designed to estimate interferon-gamma (INF-gamma) levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus (HBV and HCV) status were conducted on 20 unsplenectomized patients with gamma-thalassaemia major and 20 patients with acute myeloid leukaemia (AML) in the maintenance phase and 20 healthy subjects. Mean haemoglobin levels and red blood cell counts were significantly higher in the control group than the AML and thalassaemia groups, while white blood cell counts were significantly lower in the control group than the case groups. Two AML patients (10%) and 1 thalassaemia patient (5%) were HBV-positive, while 5% of both case groups were HCV-positive. Mean values of INF-gamma were significantly different between AML, thalassaemia major and control groups: 5517 (SD 1142) pg/mL, 1024 (SD 249) pg/mL and 2980 (SD 604) pg/mL respectively.</abstract><cop>Egypt</cop><pmid>24617130</pmid><doi>10.26719/2013.19.5.490</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1020-3397 |
| ispartof | Eastern Mediterranean health journal, 2013-05, Vol.19 (5), p.490-494 |
| issn | 1020-3397 1687-1634 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1507187944 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | beta-Thalassemia - blood beta-Thalassemia - therapy Blood Transfusion - statistics & numerical data Blood Transfusion - utilization Case-Control Studies Egypt Erythrocyte Count Hemoglobins - analysis Hepacivirus - isolation & purification Hepatitis B virus - isolation & purification Humans Interferon-gamma - blood Leukemia, Myeloid, Acute - blood Leukemia, Myeloid, Acute - therapy Leukocyte Count Transfusion Reaction |
| title | Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T03%3A25%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Quantitative%20estimation%20of%20interferon-gamma%20levels%20among%20Egyptian%20polytransfused%20haematology%20cases&rft.jtitle=Eastern%20Mediterranean%20health%20journal&rft.au=Roshdy,%20M%20N&rft.date=2013-05-01&rft.volume=19&rft.issue=5&rft.spage=490&rft.epage=494&rft.pages=490-494&rft.issn=1020-3397&rft.eissn=1687-1634&rft_id=info:doi/10.26719/2013.19.5.490&rft_dat=%3Cproquest_cross%3E1507187944%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1507187944&rft_id=info:pmid/24617130&rfr_iscdi=true |