Genetic Background Influences Nicotine-induced Conditioned Place Preference and Place Aversion in Mice

This study was designed to determine whether genetic differences influence the rewarding effects of nicotine in 4 inbred strains of mice (DBA/2, BALB/c, C3H, and C57BL/6). Nicotine (subcutaneous) induced a place preference in DBA/2 and BALB/c mice but a place aversion in C57BL/6 mice. A low dose of...

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Veröffentlicht in:Journal of Nippon Medical School 2014, Vol.81(1), pp.53-56
Hauptverfasser: Ise, Yuya, Mori, Tomohisa, Katayama, Shirou, Suzuki, Tsutomu, Wang, Tzu-Chueh
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Sprache:eng
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