QT interval measurement and correction in patients with atrial flutter: a pilot study
Abstract Background and Purpose Measurement of QT intervals during atrial flutter (AFL) is relevant to monitor the safety of drug delivery. Our aim is to compare QT and QTc intervals in AFL patients before and after catheter ablation in order to validate QT measurement during AFL. Methods 25 patient...
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Veröffentlicht in: | Journal of electrocardiology 2014-03, Vol.47 (2), p.228-235 |
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container_title | Journal of electrocardiology |
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creator | Jacquemet, V., PhD Cassani González, R., MSc Sturmer, M., MD Dubé, B., MSc Sharestan, J., MD Vinet, A., PhD Mahiddine, O., MD LeBlanc, A.R., PhD Becker, G., MD Kus, T., MD, PhD Nadeau, R., MD |
description | Abstract Background and Purpose Measurement of QT intervals during atrial flutter (AFL) is relevant to monitor the safety of drug delivery. Our aim is to compare QT and QTc intervals in AFL patients before and after catheter ablation in order to validate QT measurement during AFL. Methods 25 patients suffering from AFL underwent catheter ablation; 9 were in sinus rhythm and 16 were in AFL at the time of the procedure. Holter ECGs were continuously recorded before, during and after the procedure. In AFL signals, flutter waves were subtracted using a previously-validated deconvolution-based method. Fridericia's QTc was computed before and after ablation after hysteresis reduction. Results Comparing QTc values obtained before and after ablation showed that (1) the intervention did not significantly affect QTc, and (2) the QTc during AFL was concordant with the QTc value in sinus rhythm. Conclusion QTc can be reliably measured in patients with AFL using flutter wave subtraction and hysteresis reduction. |
doi_str_mv | 10.1016/j.jelectrocard.2013.11.002 |
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Our aim is to compare QT and QTc intervals in AFL patients before and after catheter ablation in order to validate QT measurement during AFL. Methods 25 patients suffering from AFL underwent catheter ablation; 9 were in sinus rhythm and 16 were in AFL at the time of the procedure. Holter ECGs were continuously recorded before, during and after the procedure. In AFL signals, flutter waves were subtracted using a previously-validated deconvolution-based method. Fridericia's QTc was computed before and after ablation after hysteresis reduction. Results Comparing QTc values obtained before and after ablation showed that (1) the intervention did not significantly affect QTc, and (2) the QTc during AFL was concordant with the QTc value in sinus rhythm. Conclusion QTc can be reliably measured in patients with AFL using flutter wave subtraction and hysteresis reduction.</description><identifier>ISSN: 0022-0736</identifier><identifier>EISSN: 1532-8430</identifier><identifier>DOI: 10.1016/j.jelectrocard.2013.11.002</identifier><identifier>PMID: 24360343</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Atrial flutter ; Atrial Flutter - physiopathology ; Atrial Flutter - surgery ; Cardiovascular ; Catheter ablation ; Catheter Ablation - methods ; Electrocardiography ; Electrocardiography, Ambulatory ; Female ; Heart Conduction System - physiopathology ; Humans ; Male ; Middle Aged ; Pilot Projects ; QT intervals ; Subtraction Technique</subject><ispartof>Journal of electrocardiology, 2014-03, Vol.47 (2), p.228-235</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c487t-5861ca775d0d406e55b34516d2f7f44005e81f770ef9f5c9bac8532c6994f6c73</citedby><cites>FETCH-LOGICAL-c487t-5861ca775d0d406e55b34516d2f7f44005e81f770ef9f5c9bac8532c6994f6c73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022073613005669$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24360343$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jacquemet, V., PhD</creatorcontrib><creatorcontrib>Cassani González, R., MSc</creatorcontrib><creatorcontrib>Sturmer, M., MD</creatorcontrib><creatorcontrib>Dubé, B., MSc</creatorcontrib><creatorcontrib>Sharestan, J., MD</creatorcontrib><creatorcontrib>Vinet, A., PhD</creatorcontrib><creatorcontrib>Mahiddine, O., MD</creatorcontrib><creatorcontrib>LeBlanc, A.R., PhD</creatorcontrib><creatorcontrib>Becker, G., MD</creatorcontrib><creatorcontrib>Kus, T., MD, PhD</creatorcontrib><creatorcontrib>Nadeau, R., MD</creatorcontrib><title>QT interval measurement and correction in patients with atrial flutter: a pilot study</title><title>Journal of electrocardiology</title><addtitle>J Electrocardiol</addtitle><description>Abstract Background and Purpose Measurement of QT intervals during atrial flutter (AFL) is relevant to monitor the safety of drug delivery. Our aim is to compare QT and QTc intervals in AFL patients before and after catheter ablation in order to validate QT measurement during AFL. Methods 25 patients suffering from AFL underwent catheter ablation; 9 were in sinus rhythm and 16 were in AFL at the time of the procedure. Holter ECGs were continuously recorded before, during and after the procedure. In AFL signals, flutter waves were subtracted using a previously-validated deconvolution-based method. Fridericia's QTc was computed before and after ablation after hysteresis reduction. Results Comparing QTc values obtained before and after ablation showed that (1) the intervention did not significantly affect QTc, and (2) the QTc during AFL was concordant with the QTc value in sinus rhythm. Conclusion QTc can be reliably measured in patients with AFL using flutter wave subtraction and hysteresis reduction.</description><subject>Aged</subject><subject>Atrial flutter</subject><subject>Atrial Flutter - physiopathology</subject><subject>Atrial Flutter - surgery</subject><subject>Cardiovascular</subject><subject>Catheter ablation</subject><subject>Catheter Ablation - methods</subject><subject>Electrocardiography</subject><subject>Electrocardiography, Ambulatory</subject><subject>Female</subject><subject>Heart Conduction System - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pilot Projects</subject><subject>QT intervals</subject><subject>Subtraction Technique</subject><issn>0022-0736</issn><issn>1532-8430</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUuLFTEQhYMozp3RvyDBlZtuK8_unoUgo47CgIgz65CbVGPaflyT9Mj996a5o4grVwVV59ShviLkJYOaAdOvh3rAEV2Oi7PR1xyYqBmrAfgjsmNK8KqVAh6TXenwChqhz8h5SgMAdLzhT8kZl0KDkGJH7r7c0jBnjPd2pBPatEaccM7Uzp66JcaSE5a5aOjB5lAmif4M-Ru1OYZi6cc1F_cltfQQxiXTlFd_fEae9HZM-PyhXpC7D-9vrz5WN5-vP129vamcbJtcqVYzZ5tGefASNCq1F1Ix7Xnf9FICKGxZ3zSAfdcr1-2ta8t5Tned7LVrxAV5ddp7iMuPFVM2U0gOx9HOuKzJMAVask4rWaSXJ6mLS0oRe3OIYbLxaBiYDasZzN9YzYbVMGYKxGJ-8ZCz7if0f6y_ORbBu5MAy7X3AaNJrsBy6MNG0Pgl_F_Om3_WuDHMwdnxOx4xDcsa58LTMJO4AfN1e_D2XyYKK6078Qvh06S3</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Jacquemet, V., PhD</creator><creator>Cassani González, R., MSc</creator><creator>Sturmer, M., MD</creator><creator>Dubé, B., MSc</creator><creator>Sharestan, J., MD</creator><creator>Vinet, A., PhD</creator><creator>Mahiddine, O., MD</creator><creator>LeBlanc, A.R., PhD</creator><creator>Becker, G., MD</creator><creator>Kus, T., MD, PhD</creator><creator>Nadeau, R., MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140301</creationdate><title>QT interval measurement and correction in patients with atrial flutter: a pilot study</title><author>Jacquemet, V., PhD ; Cassani González, R., MSc ; Sturmer, M., MD ; Dubé, B., MSc ; Sharestan, J., MD ; Vinet, A., PhD ; Mahiddine, O., MD ; LeBlanc, A.R., PhD ; Becker, G., MD ; Kus, T., MD, PhD ; Nadeau, R., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c487t-5861ca775d0d406e55b34516d2f7f44005e81f770ef9f5c9bac8532c6994f6c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Atrial flutter</topic><topic>Atrial Flutter - physiopathology</topic><topic>Atrial Flutter - surgery</topic><topic>Cardiovascular</topic><topic>Catheter ablation</topic><topic>Catheter Ablation - methods</topic><topic>Electrocardiography</topic><topic>Electrocardiography, Ambulatory</topic><topic>Female</topic><topic>Heart Conduction System - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pilot Projects</topic><topic>QT intervals</topic><topic>Subtraction Technique</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jacquemet, V., PhD</creatorcontrib><creatorcontrib>Cassani González, R., MSc</creatorcontrib><creatorcontrib>Sturmer, M., MD</creatorcontrib><creatorcontrib>Dubé, B., MSc</creatorcontrib><creatorcontrib>Sharestan, J., MD</creatorcontrib><creatorcontrib>Vinet, A., PhD</creatorcontrib><creatorcontrib>Mahiddine, O., MD</creatorcontrib><creatorcontrib>LeBlanc, A.R., PhD</creatorcontrib><creatorcontrib>Becker, G., MD</creatorcontrib><creatorcontrib>Kus, T., MD, PhD</creatorcontrib><creatorcontrib>Nadeau, R., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of electrocardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jacquemet, V., PhD</au><au>Cassani González, R., MSc</au><au>Sturmer, M., MD</au><au>Dubé, B., MSc</au><au>Sharestan, J., MD</au><au>Vinet, A., PhD</au><au>Mahiddine, O., MD</au><au>LeBlanc, A.R., PhD</au><au>Becker, G., MD</au><au>Kus, T., MD, PhD</au><au>Nadeau, R., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>QT interval measurement and correction in patients with atrial flutter: a pilot study</atitle><jtitle>Journal of electrocardiology</jtitle><addtitle>J Electrocardiol</addtitle><date>2014-03-01</date><risdate>2014</risdate><volume>47</volume><issue>2</issue><spage>228</spage><epage>235</epage><pages>228-235</pages><issn>0022-0736</issn><eissn>1532-8430</eissn><abstract>Abstract Background and Purpose Measurement of QT intervals during atrial flutter (AFL) is relevant to monitor the safety of drug delivery. Our aim is to compare QT and QTc intervals in AFL patients before and after catheter ablation in order to validate QT measurement during AFL. Methods 25 patients suffering from AFL underwent catheter ablation; 9 were in sinus rhythm and 16 were in AFL at the time of the procedure. Holter ECGs were continuously recorded before, during and after the procedure. In AFL signals, flutter waves were subtracted using a previously-validated deconvolution-based method. Fridericia's QTc was computed before and after ablation after hysteresis reduction. Results Comparing QTc values obtained before and after ablation showed that (1) the intervention did not significantly affect QTc, and (2) the QTc during AFL was concordant with the QTc value in sinus rhythm. Conclusion QTc can be reliably measured in patients with AFL using flutter wave subtraction and hysteresis reduction.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24360343</pmid><doi>10.1016/j.jelectrocard.2013.11.002</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Atrial flutter Atrial Flutter - physiopathology Atrial Flutter - surgery Cardiovascular Catheter ablation Catheter Ablation - methods Electrocardiography Electrocardiography, Ambulatory Female Heart Conduction System - physiopathology Humans Male Middle Aged Pilot Projects QT intervals Subtraction Technique |
title | QT interval measurement and correction in patients with atrial flutter: a pilot study |
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