Deletion of a Conserved cis-Element in the Ifng Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription: e1003969

Differentiation-dependent regulation of the Ifng cytokine gene locus in T helper (Th) cells has emerged as an excellent model for functional study of distal elements that control lineage-specific gene expression. We previously identified a cis-regulatory element located 22 kb upstream of the Ifng ge...

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Veröffentlicht in:	PLoS genetics 2014-01, Vol.10 (1)
Hauptverfasser:	Balasubramani, Anand, Winstead, Colleen J, Turner, Henrietta, Janowski, Karen M, Harbour, Stacey N, Shibata, Yoichiro, Crawford, Gregory E, Hatton, Robin D, Weaver, Casey T
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Artificial chromosomes Chromatin Epigenetics Experiments Gene expression Gene loci Genomes Lymphocytes Recruitment Stem cells Studies
Online-Zugang:	Volltext
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