Local translation in neuronal processes—in vivo tests of a “heretical hypothesis”

ABSTRACT Intracellular trafficking and localization of mRNA is a fundamental feature of living cells, suggesting that localized mRNA translation should enable subcellular regulation of the proteome. Such localized regulation may be of particular importance in highly polarized cells such as neurons,...

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Veröffentlicht in:	Developmental neurobiology (Hoboken, N.J.) N.J.), 2014-03, Vol.74 (3), p.210-217
Hauptverfasser:	Perry, Rotem B., Fainzilber, Mike
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals axon Axons - metabolism Dendrites - metabolism Humans local translation Models, Neurological nerve injury Neurons - metabolism Protein Biosynthesis regeneration retrograde transport RNA, Messenger - metabolism Sensory Receptor Cells - metabolism
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