Dose Versus pharmacokinetics for predicting tolerance to 5‐day continuous infusion of 5‐FU

This non‐randomized study reports pharmaco‐clinical data on 5‐FU administered by the widely used 5‐day continuous infusion schedule to 42 patients with metastatic colorectal cancer; 5‐FU was given by hepatic intra‐arterial route (h.i.a.) at doses ranging from 800 to 1,450 mg/m2, and by a systemic in...

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