Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy

Objectives The purpose of this paper was to determine whether microRNAs (miRNAs) involved in myocardial remodeling were differentially expressed in the blood of hypertrophic cardiomyopathy (HCM) patients, and whether circulating miRNAs correlated with the degree of left ventricular hypertrophy and f...

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Veröffentlicht in:	Journal of the American College of Cardiology 2014-03, Vol.63 (9), p.920-927
Hauptverfasser:	Roncarati, Roberta, PhD, Viviani Anselmi, Chiara, PhD, Losi, Maria Angela, MD, Papa, Laura, PhD, Cavarretta, Elena, MD, PhD, Da Costa Martins, Paula, PhD, Contaldi, Carla, MD, Saccani Jotti, Gloria, MD, Franzone, Anna, MD, Galastri, Laura, MD, Latronico, Michael V.G, Imbriaco, Massimo, MD, Esposito, Giovanni, MD, De Windt, Leon, PhD, Betocchi, Sandro, MD, Condorelli, Gianluigi, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Angiogenesis Apoptosis Biological and medical sciences Biomarkers - blood Cardiology Cardiology. Vascular system Cardiomyopathy Cardiomyopathy, Hypertrophic - blood Cardiomyopathy, Hypertrophic - genetics Cardiovascular Cardiovascular disease circulating microRNAs Drug therapy Echocardiography Female fibrosis Fibrosis - blood Fibrosis - genetics Gene expression Heart Heart attacks Heart failure Humans hypertrophic cardiomyopathy Hypertrophy - blood Hypertrophy - genetics Hypertrophy, Left Ventricular - pathology Internal Medicine Magnetic Resonance Spectroscopy Male Medical sciences MicroRNAs - blood MicroRNAs - metabolism Middle Aged myocardial remodeling Myocarditis. Cardiomyopathies Patients Physiology Real-Time Polymerase Chain Reaction ROC Curve Studies Up-Regulation Values
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