Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality
Abstract Purpose The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mor...
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| Veröffentlicht in: | Journal of critical care 2013-12, Vol.28 (6), p.975-979 |
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| creator | Cilli, Aykut, MD Erdem, Hakan, MD Karakurt, Zuhal, MD Turkan, Hulya, MD Yazicioglu-Mocin, Ozlem, MD Adiguzel, Nalan, MD Gungor, Gokay, MD Bilge, Ugur, PhD Tasci, Canturk, MD Yilmaz, Gulden, MD Oncul, Oral, MD Dogan-Celik, Aygul, MD Erdemli, Ozcan, MD Oztoprak, Nefise, MD Samur, Anil Aktas, PhD Tomak, Yakup, MD Inan, Asuman, MD Karaboga, Burcu, MD Tok, Demet, MD Temur, Sibel, MD Oksuz, Hafize, MD Senturk, Ozgur, MD Buyukkocak, Unase, MD Yilmaz-Karadag, Fatma, MD Ozcengiz, Dilek, MD Karakas, Ahmet, MD Savasci, Umit, MD Ozgen-Alpaydın, Aylin, MD Kilic, Erol, MD Elaldi, Nazif, MD Bilgic, Hayati, MD |
| description | Abstract Purpose The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. Materials and Methods An analysis was performed on data from patients with CAP hospitalized in the ICUs of 19 different hospitals in Turkey between October 2008 and January 2011. Predictors of mortality were assessed by both univariate and multivariate statistical analyses. Results Two hundred eleven patients with COPD and CAP were included. The overall ICU mortality was 23.9%. Noninvasive ventilation treatment (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.03-0.49; P = .003), hypertension (OR, 0.13; 95% CI, 0.02-0.93; P = .042), bilateral infiltration (OR, 13.92; 95% CI, 2.94-65.84; P = .001), systemic corticosteroid treatment (OR, 0.19; 95% CI, 0.35-0.96; P = .045), length of ICU stay (OR, 0.65; 95% CI, 0.47-0.89; P = .007), and duration of invasive mechanical ventilation (OR, 1.11; 95% CI, 1.01-1.22; P = .032) were independent factors related to mortality. Conclusion Noninvasive ventilation, hypertension, systemic corticosteroid treatment, and shorter ICU stay are associated with reduced mortality, whereas bilateral infiltration and longer duration of invasive mechanical ventilation are associated with increased risk of mortality in patients with COPD and CAP requiring ICU admission. |
| doi_str_mv | 10.1016/j.jcrc.2013.08.004 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1505252845</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S088394411300289X</els_id><sourcerecordid>3146118421</sourcerecordid><originalsourceid>FETCH-LOGICAL-c472t-35e8a1c161da35f1600b3b2093b1d545dcbd770eb18b5e25693a86598f1390d73</originalsourceid><addsrcrecordid>eNqFkk2L1TAUhosoznX0D7iQgBs3rSdN06Yiglz8ggHBD3AX0uTUm07bdJJ05P4Zf6spd1SYha6yyHPe5JznZNljCgUFWj8fikF7XZRAWQGiAKjuZDvKeZOLmvK72Q6EYHlbVfQsexDCAEAbxvj97KysoOEM6C77uXfTtM42HnOlr1br0ZBlxnVys1XEzmRR0eIcA_lh44Hog08XmrguRL_qaK-RLOuYaOWPxNiAKiDxuCXZ-TtRZrIhWDeT6Eg8YEqMOIetTCuPZHv5BflkwyXplY7OB9I7TybnoxrTpx5m93o1Bnx0c55nX9---bJ_n198fPdh__oi11VTxpxxFIpqWlOjGO9pDdCxroSWddTwihvdmaYB7KjoOJa8bpkSNW9FT1kLpmHn2bNT7uLd1YohyvRvjeOoZnRrkJQDL3kpKv5_tOKCioa2W-rTW-jgVj-nRhJVV21dNWKjyhOlvQvBYy8Xb6c0T0lBbqLlIDfRchMtQcgkOhU9uYleuwnNn5LfZhPw8gRgGtu1RS-DTiI1muRYR2mc_Xf-q1vlerTJvBov8Yjhbx8ylBLk523Vtk2jDKAU7Tf2CzQN0UM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1464964787</pqid></control><display><type>article</type><title>Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Cilli, Aykut, MD ; Erdem, Hakan, MD ; Karakurt, Zuhal, MD ; Turkan, Hulya, MD ; Yazicioglu-Mocin, Ozlem, MD ; Adiguzel, Nalan, MD ; Gungor, Gokay, MD ; Bilge, Ugur, PhD ; Tasci, Canturk, MD ; Yilmaz, Gulden, MD ; Oncul, Oral, MD ; Dogan-Celik, Aygul, MD ; Erdemli, Ozcan, MD ; Oztoprak, Nefise, MD ; Samur, Anil Aktas, PhD ; Tomak, Yakup, MD ; Inan, Asuman, MD ; Karaboga, Burcu, MD ; Tok, Demet, MD ; Temur, Sibel, MD ; Oksuz, Hafize, MD ; Senturk, Ozgur, MD ; Buyukkocak, Unase, MD ; Yilmaz-Karadag, Fatma, MD ; Ozcengiz, Dilek, MD ; Karakas, Ahmet, MD ; Savasci, Umit, MD ; Ozgen-Alpaydın, Aylin, MD ; Kilic, Erol, MD ; Elaldi, Nazif, MD ; Bilgic, Hayati, MD</creator><creatorcontrib>Cilli, Aykut, MD ; Erdem, Hakan, MD ; Karakurt, Zuhal, MD ; Turkan, Hulya, MD ; Yazicioglu-Mocin, Ozlem, MD ; Adiguzel, Nalan, MD ; Gungor, Gokay, MD ; Bilge, Ugur, PhD ; Tasci, Canturk, MD ; Yilmaz, Gulden, MD ; Oncul, Oral, MD ; Dogan-Celik, Aygul, MD ; Erdemli, Ozcan, MD ; Oztoprak, Nefise, MD ; Samur, Anil Aktas, PhD ; Tomak, Yakup, MD ; Inan, Asuman, MD ; Karaboga, Burcu, MD ; Tok, Demet, MD ; Temur, Sibel, MD ; Oksuz, Hafize, MD ; Senturk, Ozgur, MD ; Buyukkocak, Unase, MD ; Yilmaz-Karadag, Fatma, MD ; Ozcengiz, Dilek, MD ; Karakas, Ahmet, MD ; Savasci, Umit, MD ; Ozgen-Alpaydın, Aylin, MD ; Kilic, Erol, MD ; Elaldi, Nazif, MD ; Bilgic, Hayati, MD</creatorcontrib><description>Abstract Purpose The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. Materials and Methods An analysis was performed on data from patients with CAP hospitalized in the ICUs of 19 different hospitals in Turkey between October 2008 and January 2011. Predictors of mortality were assessed by both univariate and multivariate statistical analyses. Results Two hundred eleven patients with COPD and CAP were included. The overall ICU mortality was 23.9%. Noninvasive ventilation treatment (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.03-0.49; P = .003), hypertension (OR, 0.13; 95% CI, 0.02-0.93; P = .042), bilateral infiltration (OR, 13.92; 95% CI, 2.94-65.84; P = .001), systemic corticosteroid treatment (OR, 0.19; 95% CI, 0.35-0.96; P = .045), length of ICU stay (OR, 0.65; 95% CI, 0.47-0.89; P = .007), and duration of invasive mechanical ventilation (OR, 1.11; 95% CI, 1.01-1.22; P = .032) were independent factors related to mortality. Conclusion Noninvasive ventilation, hypertension, systemic corticosteroid treatment, and shorter ICU stay are associated with reduced mortality, whereas bilateral infiltration and longer duration of invasive mechanical ventilation are associated with increased risk of mortality in patients with COPD and CAP requiring ICU admission.</description><identifier>ISSN: 0883-9441</identifier><identifier>EISSN: 1557-8615</identifier><identifier>DOI: 10.1016/j.jcrc.2013.08.004</identifier><identifier>PMID: 24075301</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adrenal Cortex Hormones - administration & dosage ; Aged ; Chronic obstructive pulmonary disease ; Community-Acquired Infections - complications ; Community-Acquired Infections - mortality ; Community-acquired pneumonia ; COPD ; Critical Care ; Drug therapy ; Female ; Health Status Indicators ; Hospital Mortality ; Humans ; Hypertension - complications ; Intensive care ; Intensive care unit ; Intensive Care Units ; Length of Stay - statistics & numerical data ; Male ; Mortality ; Patients ; Pneumonia ; Pneumonia - complications ; Pneumonia - mortality ; Predictive Value of Tests ; Pulmonary Disease, Chronic Obstructive - complications ; Pulmonary Disease, Chronic Obstructive - mortality ; Respiration, Artificial - adverse effects ; Risk Factors ; Severity of Illness Index ; Turkey - epidemiology</subject><ispartof>Journal of critical care, 2013-12, Vol.28 (6), p.975-979</ispartof><rights>Elsevier Inc.</rights><rights>2013 Elsevier Inc.</rights><rights>2013.</rights><rights>Copyright Elsevier Limited Dec 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-35e8a1c161da35f1600b3b2093b1d545dcbd770eb18b5e25693a86598f1390d73</citedby><cites>FETCH-LOGICAL-c472t-35e8a1c161da35f1600b3b2093b1d545dcbd770eb18b5e25693a86598f1390d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S088394411300289X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24075301$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cilli, Aykut, MD</creatorcontrib><creatorcontrib>Erdem, Hakan, MD</creatorcontrib><creatorcontrib>Karakurt, Zuhal, MD</creatorcontrib><creatorcontrib>Turkan, Hulya, MD</creatorcontrib><creatorcontrib>Yazicioglu-Mocin, Ozlem, MD</creatorcontrib><creatorcontrib>Adiguzel, Nalan, MD</creatorcontrib><creatorcontrib>Gungor, Gokay, MD</creatorcontrib><creatorcontrib>Bilge, Ugur, PhD</creatorcontrib><creatorcontrib>Tasci, Canturk, MD</creatorcontrib><creatorcontrib>Yilmaz, Gulden, MD</creatorcontrib><creatorcontrib>Oncul, Oral, MD</creatorcontrib><creatorcontrib>Dogan-Celik, Aygul, MD</creatorcontrib><creatorcontrib>Erdemli, Ozcan, MD</creatorcontrib><creatorcontrib>Oztoprak, Nefise, MD</creatorcontrib><creatorcontrib>Samur, Anil Aktas, PhD</creatorcontrib><creatorcontrib>Tomak, Yakup, MD</creatorcontrib><creatorcontrib>Inan, Asuman, MD</creatorcontrib><creatorcontrib>Karaboga, Burcu, MD</creatorcontrib><creatorcontrib>Tok, Demet, MD</creatorcontrib><creatorcontrib>Temur, Sibel, MD</creatorcontrib><creatorcontrib>Oksuz, Hafize, MD</creatorcontrib><creatorcontrib>Senturk, Ozgur, MD</creatorcontrib><creatorcontrib>Buyukkocak, Unase, MD</creatorcontrib><creatorcontrib>Yilmaz-Karadag, Fatma, MD</creatorcontrib><creatorcontrib>Ozcengiz, Dilek, MD</creatorcontrib><creatorcontrib>Karakas, Ahmet, MD</creatorcontrib><creatorcontrib>Savasci, Umit, MD</creatorcontrib><creatorcontrib>Ozgen-Alpaydın, Aylin, MD</creatorcontrib><creatorcontrib>Kilic, Erol, MD</creatorcontrib><creatorcontrib>Elaldi, Nazif, MD</creatorcontrib><creatorcontrib>Bilgic, Hayati, MD</creatorcontrib><title>Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality</title><title>Journal of critical care</title><addtitle>J Crit Care</addtitle><description>Abstract Purpose The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. Materials and Methods An analysis was performed on data from patients with CAP hospitalized in the ICUs of 19 different hospitals in Turkey between October 2008 and January 2011. Predictors of mortality were assessed by both univariate and multivariate statistical analyses. Results Two hundred eleven patients with COPD and CAP were included. The overall ICU mortality was 23.9%. Noninvasive ventilation treatment (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.03-0.49; P = .003), hypertension (OR, 0.13; 95% CI, 0.02-0.93; P = .042), bilateral infiltration (OR, 13.92; 95% CI, 2.94-65.84; P = .001), systemic corticosteroid treatment (OR, 0.19; 95% CI, 0.35-0.96; P = .045), length of ICU stay (OR, 0.65; 95% CI, 0.47-0.89; P = .007), and duration of invasive mechanical ventilation (OR, 1.11; 95% CI, 1.01-1.22; P = .032) were independent factors related to mortality. Conclusion Noninvasive ventilation, hypertension, systemic corticosteroid treatment, and shorter ICU stay are associated with reduced mortality, whereas bilateral infiltration and longer duration of invasive mechanical ventilation are associated with increased risk of mortality in patients with COPD and CAP requiring ICU admission.</description><subject>Adrenal Cortex Hormones - administration & dosage</subject><subject>Aged</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Community-Acquired Infections - complications</subject><subject>Community-Acquired Infections - mortality</subject><subject>Community-acquired pneumonia</subject><subject>COPD</subject><subject>Critical Care</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Health Status Indicators</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Intensive care</subject><subject>Intensive care unit</subject><subject>Intensive Care Units</subject><subject>Length of Stay - statistics & numerical data</subject><subject>Male</subject><subject>Mortality</subject><subject>Patients</subject><subject>Pneumonia</subject><subject>Pneumonia - complications</subject><subject>Pneumonia - mortality</subject><subject>Predictive Value of Tests</subject><subject>Pulmonary Disease, Chronic Obstructive - complications</subject><subject>Pulmonary Disease, Chronic Obstructive - mortality</subject><subject>Respiration, Artificial - adverse effects</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Turkey - epidemiology</subject><issn>0883-9441</issn><issn>1557-8615</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkk2L1TAUhosoznX0D7iQgBs3rSdN06Yiglz8ggHBD3AX0uTUm07bdJJ05P4Zf6spd1SYha6yyHPe5JznZNljCgUFWj8fikF7XZRAWQGiAKjuZDvKeZOLmvK72Q6EYHlbVfQsexDCAEAbxvj97KysoOEM6C77uXfTtM42HnOlr1br0ZBlxnVys1XEzmRR0eIcA_lh44Hog08XmrguRL_qaK-RLOuYaOWPxNiAKiDxuCXZ-TtRZrIhWDeT6Eg8YEqMOIetTCuPZHv5BflkwyXplY7OB9I7TybnoxrTpx5m93o1Bnx0c55nX9---bJ_n198fPdh__oi11VTxpxxFIpqWlOjGO9pDdCxroSWddTwihvdmaYB7KjoOJa8bpkSNW9FT1kLpmHn2bNT7uLd1YohyvRvjeOoZnRrkJQDL3kpKv5_tOKCioa2W-rTW-jgVj-nRhJVV21dNWKjyhOlvQvBYy8Xb6c0T0lBbqLlIDfRchMtQcgkOhU9uYleuwnNn5LfZhPw8gRgGtu1RS-DTiI1muRYR2mc_Xf-q1vlerTJvBov8Yjhbx8ylBLk523Vtk2jDKAU7Tf2CzQN0UM</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Cilli, Aykut, MD</creator><creator>Erdem, Hakan, MD</creator><creator>Karakurt, Zuhal, MD</creator><creator>Turkan, Hulya, MD</creator><creator>Yazicioglu-Mocin, Ozlem, MD</creator><creator>Adiguzel, Nalan, MD</creator><creator>Gungor, Gokay, MD</creator><creator>Bilge, Ugur, PhD</creator><creator>Tasci, Canturk, MD</creator><creator>Yilmaz, Gulden, MD</creator><creator>Oncul, Oral, MD</creator><creator>Dogan-Celik, Aygul, MD</creator><creator>Erdemli, Ozcan, MD</creator><creator>Oztoprak, Nefise, MD</creator><creator>Samur, Anil Aktas, PhD</creator><creator>Tomak, Yakup, MD</creator><creator>Inan, Asuman, MD</creator><creator>Karaboga, Burcu, MD</creator><creator>Tok, Demet, MD</creator><creator>Temur, Sibel, MD</creator><creator>Oksuz, Hafize, MD</creator><creator>Senturk, Ozgur, MD</creator><creator>Buyukkocak, Unase, MD</creator><creator>Yilmaz-Karadag, Fatma, MD</creator><creator>Ozcengiz, Dilek, MD</creator><creator>Karakas, Ahmet, MD</creator><creator>Savasci, Umit, MD</creator><creator>Ozgen-Alpaydın, Aylin, MD</creator><creator>Kilic, Erol, MD</creator><creator>Elaldi, Nazif, MD</creator><creator>Bilgic, Hayati, MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20131201</creationdate><title>Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality</title><author>Cilli, Aykut, MD ; Erdem, Hakan, MD ; Karakurt, Zuhal, MD ; Turkan, Hulya, MD ; Yazicioglu-Mocin, Ozlem, MD ; Adiguzel, Nalan, MD ; Gungor, Gokay, MD ; Bilge, Ugur, PhD ; Tasci, Canturk, MD ; Yilmaz, Gulden, MD ; Oncul, Oral, MD ; Dogan-Celik, Aygul, MD ; Erdemli, Ozcan, MD ; Oztoprak, Nefise, MD ; Samur, Anil Aktas, PhD ; Tomak, Yakup, MD ; Inan, Asuman, MD ; Karaboga, Burcu, MD ; Tok, Demet, MD ; Temur, Sibel, MD ; Oksuz, Hafize, MD ; Senturk, Ozgur, MD ; Buyukkocak, Unase, MD ; Yilmaz-Karadag, Fatma, MD ; Ozcengiz, Dilek, MD ; Karakas, Ahmet, MD ; Savasci, Umit, MD ; Ozgen-Alpaydın, Aylin, MD ; Kilic, Erol, MD ; Elaldi, Nazif, MD ; Bilgic, Hayati, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-35e8a1c161da35f1600b3b2093b1d545dcbd770eb18b5e25693a86598f1390d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adrenal Cortex Hormones - administration & dosage</topic><topic>Aged</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Community-Acquired Infections - complications</topic><topic>Community-Acquired Infections - mortality</topic><topic>Community-acquired pneumonia</topic><topic>COPD</topic><topic>Critical Care</topic><topic>Drug therapy</topic><topic>Female</topic><topic>Health Status Indicators</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Intensive care</topic><topic>Intensive care unit</topic><topic>Intensive Care Units</topic><topic>Length of Stay - statistics & numerical data</topic><topic>Male</topic><topic>Mortality</topic><topic>Patients</topic><topic>Pneumonia</topic><topic>Pneumonia - complications</topic><topic>Pneumonia - mortality</topic><topic>Predictive Value of Tests</topic><topic>Pulmonary Disease, Chronic Obstructive - complications</topic><topic>Pulmonary Disease, Chronic Obstructive - mortality</topic><topic>Respiration, Artificial - adverse effects</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Turkey - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cilli, Aykut, MD</creatorcontrib><creatorcontrib>Erdem, Hakan, MD</creatorcontrib><creatorcontrib>Karakurt, Zuhal, MD</creatorcontrib><creatorcontrib>Turkan, Hulya, MD</creatorcontrib><creatorcontrib>Yazicioglu-Mocin, Ozlem, MD</creatorcontrib><creatorcontrib>Adiguzel, Nalan, MD</creatorcontrib><creatorcontrib>Gungor, Gokay, MD</creatorcontrib><creatorcontrib>Bilge, Ugur, PhD</creatorcontrib><creatorcontrib>Tasci, Canturk, MD</creatorcontrib><creatorcontrib>Yilmaz, Gulden, MD</creatorcontrib><creatorcontrib>Oncul, Oral, MD</creatorcontrib><creatorcontrib>Dogan-Celik, Aygul, MD</creatorcontrib><creatorcontrib>Erdemli, Ozcan, MD</creatorcontrib><creatorcontrib>Oztoprak, Nefise, MD</creatorcontrib><creatorcontrib>Samur, Anil Aktas, PhD</creatorcontrib><creatorcontrib>Tomak, Yakup, MD</creatorcontrib><creatorcontrib>Inan, Asuman, MD</creatorcontrib><creatorcontrib>Karaboga, Burcu, MD</creatorcontrib><creatorcontrib>Tok, Demet, MD</creatorcontrib><creatorcontrib>Temur, Sibel, MD</creatorcontrib><creatorcontrib>Oksuz, Hafize, MD</creatorcontrib><creatorcontrib>Senturk, Ozgur, MD</creatorcontrib><creatorcontrib>Buyukkocak, Unase, MD</creatorcontrib><creatorcontrib>Yilmaz-Karadag, Fatma, MD</creatorcontrib><creatorcontrib>Ozcengiz, Dilek, MD</creatorcontrib><creatorcontrib>Karakas, Ahmet, MD</creatorcontrib><creatorcontrib>Savasci, Umit, MD</creatorcontrib><creatorcontrib>Ozgen-Alpaydın, Aylin, MD</creatorcontrib><creatorcontrib>Kilic, Erol, MD</creatorcontrib><creatorcontrib>Elaldi, Nazif, MD</creatorcontrib><creatorcontrib>Bilgic, Hayati, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of critical care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cilli, Aykut, MD</au><au>Erdem, Hakan, MD</au><au>Karakurt, Zuhal, MD</au><au>Turkan, Hulya, MD</au><au>Yazicioglu-Mocin, Ozlem, MD</au><au>Adiguzel, Nalan, MD</au><au>Gungor, Gokay, MD</au><au>Bilge, Ugur, PhD</au><au>Tasci, Canturk, MD</au><au>Yilmaz, Gulden, MD</au><au>Oncul, Oral, MD</au><au>Dogan-Celik, Aygul, MD</au><au>Erdemli, Ozcan, MD</au><au>Oztoprak, Nefise, MD</au><au>Samur, Anil Aktas, PhD</au><au>Tomak, Yakup, MD</au><au>Inan, Asuman, MD</au><au>Karaboga, Burcu, MD</au><au>Tok, Demet, MD</au><au>Temur, Sibel, MD</au><au>Oksuz, Hafize, MD</au><au>Senturk, Ozgur, MD</au><au>Buyukkocak, Unase, MD</au><au>Yilmaz-Karadag, Fatma, MD</au><au>Ozcengiz, Dilek, MD</au><au>Karakas, Ahmet, MD</au><au>Savasci, Umit, MD</au><au>Ozgen-Alpaydın, Aylin, MD</au><au>Kilic, Erol, MD</au><au>Elaldi, Nazif, MD</au><au>Bilgic, Hayati, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality</atitle><jtitle>Journal of critical care</jtitle><addtitle>J Crit Care</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>28</volume><issue>6</issue><spage>975</spage><epage>979</epage><pages>975-979</pages><issn>0883-9441</issn><eissn>1557-8615</eissn><abstract>Abstract Purpose The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. Materials and Methods An analysis was performed on data from patients with CAP hospitalized in the ICUs of 19 different hospitals in Turkey between October 2008 and January 2011. Predictors of mortality were assessed by both univariate and multivariate statistical analyses. Results Two hundred eleven patients with COPD and CAP were included. The overall ICU mortality was 23.9%. Noninvasive ventilation treatment (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.03-0.49; P = .003), hypertension (OR, 0.13; 95% CI, 0.02-0.93; P = .042), bilateral infiltration (OR, 13.92; 95% CI, 2.94-65.84; P = .001), systemic corticosteroid treatment (OR, 0.19; 95% CI, 0.35-0.96; P = .045), length of ICU stay (OR, 0.65; 95% CI, 0.47-0.89; P = .007), and duration of invasive mechanical ventilation (OR, 1.11; 95% CI, 1.01-1.22; P = .032) were independent factors related to mortality. Conclusion Noninvasive ventilation, hypertension, systemic corticosteroid treatment, and shorter ICU stay are associated with reduced mortality, whereas bilateral infiltration and longer duration of invasive mechanical ventilation are associated with increased risk of mortality in patients with COPD and CAP requiring ICU admission.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24075301</pmid><doi>10.1016/j.jcrc.2013.08.004</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0883-9441 |
| ispartof | Journal of critical care, 2013-12, Vol.28 (6), p.975-979 |
| issn | 0883-9441 1557-8615 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1505252845 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adrenal Cortex Hormones - administration & dosage Aged Chronic obstructive pulmonary disease Community-Acquired Infections - complications Community-Acquired Infections - mortality Community-acquired pneumonia COPD Critical Care Drug therapy Female Health Status Indicators Hospital Mortality Humans Hypertension - complications Intensive care Intensive care unit Intensive Care Units Length of Stay - statistics & numerical data Male Mortality Patients Pneumonia Pneumonia - complications Pneumonia - mortality Predictive Value of Tests Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - mortality Respiration, Artificial - adverse effects Risk Factors Severity of Illness Index Turkey - epidemiology |
| title | Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality |
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