Multimodal molecular imaging of integrin αvβ3 for in vivo detection of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. Late detection of then nonresectable or metastasized tumors emphasizes the need for novel imaging approaches. Here, we report on so far nonexploited potentials of αvβ3 integrin-targeted molecular imaging technologies for detection of PDAC...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2014-03, Vol.55 (3), p.446-451
Hauptverfasser:	Trajkovic-Arsic, Marija, Mohajerani, Pouyan, Sarantopoulos, Athanasios, Kalideris, Evdokia, Steiger, Katja, Esposito, Irene, Ma, Xiaopeng, Themelis, George, Burton, Neal, Michalski, Christoph W, Kleeff, Jörg, Stangl, Stefan, Beer, Ambros J, Pohle, Karolin, Wester, Hans-Jürgen, Schmid, Roland M, Braren, Rickmer, Ntziachristos, Vasilis, Siveke, Jens T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - diagnostic imaging Adenocarcinoma - metabolism Adenocarcinoma - surgery Animals Cell Line, Tumor Feasibility Studies Female Gene Expression Regulation, Neoplastic Humans Integrin alphaVbeta3 - metabolism Intraoperative Period Mice Multimodal Imaging Optical Imaging Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - surgery Positron-Emission Tomography Tomography
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