Population genetic data of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS STR loci in four Canadian populations
Allele frequencies and forensically relevant population statistics were estimated for the short tandem repeat (STR) loci of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS amplification kits, including D2S1338, D19S433, Penta D, and Penta E, for three First Nations Aboriginal populations and fo...
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| Veröffentlicht in: | International journal of legal medicine 2014-03, Vol.128 (2), p.277-278 |
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| container_title | International journal of legal medicine |
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| creator | Laurin, Nancy Milot, Emmanuel |
| description | Allele frequencies and forensically relevant population statistics were estimated for the short tandem repeat (STR) loci of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS amplification kits, including D2S1338, D19S433, Penta D, and Penta E, for three First Nations Aboriginal populations and for Caucasians in Canada. The cumulative power of discrimination was ≥0.999999999999984 and the cumulative power of exclusion was ≥0.999929363 for both amplification systems in all populations. No significant departure from Hardy–Weinberg equilibrium was detected for D2S1338, D19S433, Penta D, and Penta E or the 13 Combined DNA Index System core STR loci after correction for multiple testing. Significant genetic diversity was observed between these four populations. Comparison with published frequency data for other populations is also presented. |
| doi_str_mv | 10.1007/s00414-013-0899-3 |
| format | Article |
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The cumulative power of discrimination was ≥0.999999999999984 and the cumulative power of exclusion was ≥0.999929363 for both amplification systems in all populations. No significant departure from Hardy–Weinberg equilibrium was detected for D2S1338, D19S433, Penta D, and Penta E or the 13 Combined DNA Index System core STR loci after correction for multiple testing. Significant genetic diversity was observed between these four populations. 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The cumulative power of discrimination was ≥0.999999999999984 and the cumulative power of exclusion was ≥0.999929363 for both amplification systems in all populations. No significant departure from Hardy–Weinberg equilibrium was detected for D2S1338, D19S433, Penta D, and Penta E or the 13 Combined DNA Index System core STR loci after correction for multiple testing. Significant genetic diversity was observed between these four populations. Comparison with published frequency data for other populations is also presented.</description><subject>European Continental Ancestry Group - genetics</subject><subject>Female</subject><subject>Forensic Medicine</subject><subject>Gene Frequency - genetics</subject><subject>Genetic Variation - genetics</subject><subject>Genetics, Population</subject><subject>Genotype</subject><subject>Humans</subject><subject>Indians, North American - genetics</subject><subject>Male</subject><subject>Medical Law</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Microsatellite Repeats - genetics</subject><subject>Polymerase Chain Reaction</subject><subject>Population Data</subject><issn>0937-9827</issn><issn>1437-1596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFu1TAQhi1ERR8tB2CDvGQT8MR2Ei-rJ0orVeKJtmvLicfFVZ4d7EQF1r1B78EhOAonwU-vdNmVx55v_pE_Qt4C-wCMtR8zYwJExYBXrFOq4i_ICgRvK5CqeUlWTJVadXV7SF7nfMsYtE0rX5HDmitRd51ckV-bOC2jmX0M9AYDzn6g1syGRkfnb0hPttPp3_uHy6uvf37Tc4th9s6PmMptMy6ZmmDpJt5h2oz4ozxCQ88uacHpGAdPfaAuLomuTTDWm0Cnp3X5mBw4M2Z883gekevTT1frs-riy-fz9clFNfBa8qprneR9I2UteiWcMMr2CgQKcGywxgC3tXOqafnAat701vXKQYcAyNXQKn5E3u9zpxS_L5hnvfV5wHE0AeOSNUgmhOw44wWFPTqkmHNCp6fktyb91MD0TrneK9dFud4p17uZd4_xS79F-zTx33EB6j2QSyvcYNK3RUkoX34m9R87OI6T</recordid><startdate>201403</startdate><enddate>201403</enddate><creator>Laurin, Nancy</creator><creator>Milot, Emmanuel</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201403</creationdate><title>Population genetic data of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS STR loci in four Canadian populations</title><author>Laurin, Nancy ; Milot, Emmanuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3253-87f53b65524b94f4a9db914e41f0cdaa13d2ff9673c0236bdfb9f18e11e39c793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>European Continental Ancestry Group - genetics</topic><topic>Female</topic><topic>Forensic Medicine</topic><topic>Gene Frequency - genetics</topic><topic>Genetic Variation - genetics</topic><topic>Genetics, Population</topic><topic>Genotype</topic><topic>Humans</topic><topic>Indians, North American - genetics</topic><topic>Male</topic><topic>Medical Law</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Microsatellite Repeats - genetics</topic><topic>Polymerase Chain Reaction</topic><topic>Population Data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Laurin, Nancy</creatorcontrib><creatorcontrib>Milot, Emmanuel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of legal medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Laurin, Nancy</au><au>Milot, Emmanuel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Population genetic data of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS STR loci in four Canadian populations</atitle><jtitle>International journal of legal medicine</jtitle><stitle>Int J Legal Med</stitle><addtitle>Int J Legal Med</addtitle><date>2014-03</date><risdate>2014</risdate><volume>128</volume><issue>2</issue><spage>277</spage><epage>278</epage><pages>277-278</pages><issn>0937-9827</issn><eissn>1437-1596</eissn><abstract>Allele frequencies and forensically relevant population statistics were estimated for the short tandem repeat (STR) loci of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS amplification kits, including D2S1338, D19S433, Penta D, and Penta E, for three First Nations Aboriginal populations and for Caucasians in Canada. 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| identifier | ISSN: 0937-9827 |
| ispartof | International journal of legal medicine, 2014-03, Vol.128 (2), p.277-278 |
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| language | eng |
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| source | HeinOnline; MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | European Continental Ancestry Group - genetics Female Forensic Medicine Gene Frequency - genetics Genetic Variation - genetics Genetics, Population Genotype Humans Indians, North American - genetics Male Medical Law Medicine Medicine & Public Health Microsatellite Repeats - genetics Polymerase Chain Reaction Population Data |
| title | Population genetic data of the AmpFℓSTR® Identifiler® Plus and PowerPlex® 16 HS STR loci in four Canadian populations |
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