A comparison of biphasic insulin aspart and insulin glargine administered with oral antidiabetic drugs in type 2 diabetes mellitus - a systematic review and meta-analysis

Summary Objective It is uncertain whether the addition of biphasic insulin analogues to oral antidiabetic drugs (OADs) is as effective and safe as basal insulin in patients with type 2 diabetes mellitus (T2DM). We performed a systematic review to compare glycaemic control and selected clinical outco...

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Veröffentlicht in:	International journal of clinical practice (Esher) 2014-03, Vol.68 (3), p.304-313
Hauptverfasser:	Rys, P., Wojciechowski, P., Siejka, S., Małecki, P., Hak, Ł., Malecki, M. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Biphasic Insulins - administration & dosage Biphasic Insulins - adverse effects Blood Glucose - metabolism Clinical outcomes Comparative studies Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Drug therapy Drug Therapy, Combination Fasting - blood Female Glycated Hemoglobin A - drug effects Glycated Hemoglobin A - metabolism Humans Hypoglycemia - chemically induced Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - adverse effects Insulin Aspart - administration & dosage Insulin Aspart - adverse effects Insulin Glargine Insulin, Isophane - administration & dosage Insulin, Isophane - adverse effects Insulin, Long-Acting - administration & dosage Insulin, Long-Acting - adverse effects Male Middle Aged Postprandial Period Randomized Controlled Trials as Topic Systematic review Treatment Outcome Weight Gain - drug effects
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