Potential environmental implications of nano-enabled medical applications: critical review

The application of nanotechnology and nanoscience for medical purposes is anticipated to make significant contributions to enhance human health in the coming decades. However, the possible future mass production and use of these medical innovations exhibiting novel and multifunctional properties wil...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Environmental science--processes & impacts 2013-01, Vol.15 (1), p.123-144
Hauptverfasser: Mahapatra, Indrani, Clark, J, Dobson, Peter J, Owen, Richard, Lead, Jamie R
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 144
container_issue 1
container_start_page 123
container_title Environmental science--processes & impacts
container_volume 15
creator Mahapatra, Indrani
Clark, J
Dobson, Peter J
Owen, Richard
Lead, Jamie R
description The application of nanotechnology and nanoscience for medical purposes is anticipated to make significant contributions to enhance human health in the coming decades. However, the possible future mass production and use of these medical innovations exhibiting novel and multifunctional properties will very likely lead to discharges into the environment giving rise to potentially new environmental hazards and risks. To date, the sources, the release form and environmental fate and exposure of nano-enabled medical products have not been investigated and little or no data exists, although there are a small number of currently approved medical applications and a number in clinical trials. This paper discusses the current technological and regulatory landscape and potential hazards and risks to the environment of nano-enabled medical products, data gaps and gives tentative suggestions relating to possible environmental hotspots. This review paper presents a framework to understand environmental issues relating to nanomedicines and our ability to control such issues.
doi_str_mv 10.1039/c2em30640a
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1504454140</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1504454140</sourcerecordid><originalsourceid>FETCH-LOGICAL-c371t-e4c50c0d2be3a8df67dc8e1a5e60ea0035cf2e61372c7bd929cd2318f0950d393</originalsourceid><addsrcrecordid>eNp90c9LwzAUB_AgihtzF-9KvYlQfUma_vA2xvwBEz3oxUvJkleItE1Nuon_vXGb281ckpf34UG-IeSUwjUFXtwohg2HNAF5QIYMBMRZXojD3TnPBmTs_QeElQuai_SYDFgiCpZwNiTvL7bHtjeyjrBdGWfbJpShMk1XGyV7Y1sf2SpqZWtjbOWiRh01qEOvjmS3R7eRcqZfXztcGfw6IUeVrD2Ot_uIvN3NXqcP8fz5_nE6mceKZ7SPMVECFGi2QC5zXaWZVjlSKTAFlABcqIphSnnGVLbQBSuUZpzmFRQCNC_4iFxu5nbOfi7R92VjvMK6li3apS-pgCQRCU0g0KsNVc5677AqO2ca6b5LCuVvnOWUzZ7WcU4CPt_OXS7Cg3f0L7wALjbAebXr7v-j7HQVzNl_hv8AJnWGMg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1504454140</pqid></control><display><type>article</type><title>Potential environmental implications of nano-enabled medical applications: critical review</title><source>MEDLINE</source><source>Royal Society Of Chemistry Journals</source><source>Alma/SFX Local Collection</source><creator>Mahapatra, Indrani ; Clark, J ; Dobson, Peter J ; Owen, Richard ; Lead, Jamie R</creator><creatorcontrib>Mahapatra, Indrani ; Clark, J ; Dobson, Peter J ; Owen, Richard ; Lead, Jamie R</creatorcontrib><description>The application of nanotechnology and nanoscience for medical purposes is anticipated to make significant contributions to enhance human health in the coming decades. However, the possible future mass production and use of these medical innovations exhibiting novel and multifunctional properties will very likely lead to discharges into the environment giving rise to potentially new environmental hazards and risks. To date, the sources, the release form and environmental fate and exposure of nano-enabled medical products have not been investigated and little or no data exists, although there are a small number of currently approved medical applications and a number in clinical trials. This paper discusses the current technological and regulatory landscape and potential hazards and risks to the environment of nano-enabled medical products, data gaps and gives tentative suggestions relating to possible environmental hotspots. This review paper presents a framework to understand environmental issues relating to nanomedicines and our ability to control such issues.</description><identifier>ISSN: 2050-7887</identifier><identifier>EISSN: 2050-7895</identifier><identifier>DOI: 10.1039/c2em30640a</identifier><identifier>PMID: 24592432</identifier><language>eng</language><publisher>England</publisher><subject>Drug and Narcotic Control ; Drug Delivery Systems ; Environmental Policy ; Environmental Pollutants ; Nanoparticles ; Pharmaceutical Preparations ; Risk Assessment</subject><ispartof>Environmental science--processes &amp; impacts, 2013-01, Vol.15 (1), p.123-144</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-e4c50c0d2be3a8df67dc8e1a5e60ea0035cf2e61372c7bd929cd2318f0950d393</citedby><cites>FETCH-LOGICAL-c371t-e4c50c0d2be3a8df67dc8e1a5e60ea0035cf2e61372c7bd929cd2318f0950d393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24592432$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mahapatra, Indrani</creatorcontrib><creatorcontrib>Clark, J</creatorcontrib><creatorcontrib>Dobson, Peter J</creatorcontrib><creatorcontrib>Owen, Richard</creatorcontrib><creatorcontrib>Lead, Jamie R</creatorcontrib><title>Potential environmental implications of nano-enabled medical applications: critical review</title><title>Environmental science--processes &amp; impacts</title><addtitle>Environ Sci Process Impacts</addtitle><description>The application of nanotechnology and nanoscience for medical purposes is anticipated to make significant contributions to enhance human health in the coming decades. However, the possible future mass production and use of these medical innovations exhibiting novel and multifunctional properties will very likely lead to discharges into the environment giving rise to potentially new environmental hazards and risks. To date, the sources, the release form and environmental fate and exposure of nano-enabled medical products have not been investigated and little or no data exists, although there are a small number of currently approved medical applications and a number in clinical trials. This paper discusses the current technological and regulatory landscape and potential hazards and risks to the environment of nano-enabled medical products, data gaps and gives tentative suggestions relating to possible environmental hotspots. This review paper presents a framework to understand environmental issues relating to nanomedicines and our ability to control such issues.</description><subject>Drug and Narcotic Control</subject><subject>Drug Delivery Systems</subject><subject>Environmental Policy</subject><subject>Environmental Pollutants</subject><subject>Nanoparticles</subject><subject>Pharmaceutical Preparations</subject><subject>Risk Assessment</subject><issn>2050-7887</issn><issn>2050-7895</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90c9LwzAUB_AgihtzF-9KvYlQfUma_vA2xvwBEz3oxUvJkleItE1Nuon_vXGb281ckpf34UG-IeSUwjUFXtwohg2HNAF5QIYMBMRZXojD3TnPBmTs_QeElQuai_SYDFgiCpZwNiTvL7bHtjeyjrBdGWfbJpShMk1XGyV7Y1sf2SpqZWtjbOWiRh01qEOvjmS3R7eRcqZfXztcGfw6IUeVrD2Ot_uIvN3NXqcP8fz5_nE6mceKZ7SPMVECFGi2QC5zXaWZVjlSKTAFlABcqIphSnnGVLbQBSuUZpzmFRQCNC_4iFxu5nbOfi7R92VjvMK6li3apS-pgCQRCU0g0KsNVc5677AqO2ca6b5LCuVvnOWUzZ7WcU4CPt_OXS7Cg3f0L7wALjbAebXr7v-j7HQVzNl_hv8AJnWGMg</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Mahapatra, Indrani</creator><creator>Clark, J</creator><creator>Dobson, Peter J</creator><creator>Owen, Richard</creator><creator>Lead, Jamie R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130101</creationdate><title>Potential environmental implications of nano-enabled medical applications: critical review</title><author>Mahapatra, Indrani ; Clark, J ; Dobson, Peter J ; Owen, Richard ; Lead, Jamie R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-e4c50c0d2be3a8df67dc8e1a5e60ea0035cf2e61372c7bd929cd2318f0950d393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Drug and Narcotic Control</topic><topic>Drug Delivery Systems</topic><topic>Environmental Policy</topic><topic>Environmental Pollutants</topic><topic>Nanoparticles</topic><topic>Pharmaceutical Preparations</topic><topic>Risk Assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mahapatra, Indrani</creatorcontrib><creatorcontrib>Clark, J</creatorcontrib><creatorcontrib>Dobson, Peter J</creatorcontrib><creatorcontrib>Owen, Richard</creatorcontrib><creatorcontrib>Lead, Jamie R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Environmental science--processes &amp; impacts</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mahapatra, Indrani</au><au>Clark, J</au><au>Dobson, Peter J</au><au>Owen, Richard</au><au>Lead, Jamie R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potential environmental implications of nano-enabled medical applications: critical review</atitle><jtitle>Environmental science--processes &amp; impacts</jtitle><addtitle>Environ Sci Process Impacts</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>15</volume><issue>1</issue><spage>123</spage><epage>144</epage><pages>123-144</pages><issn>2050-7887</issn><eissn>2050-7895</eissn><abstract>The application of nanotechnology and nanoscience for medical purposes is anticipated to make significant contributions to enhance human health in the coming decades. However, the possible future mass production and use of these medical innovations exhibiting novel and multifunctional properties will very likely lead to discharges into the environment giving rise to potentially new environmental hazards and risks. To date, the sources, the release form and environmental fate and exposure of nano-enabled medical products have not been investigated and little or no data exists, although there are a small number of currently approved medical applications and a number in clinical trials. This paper discusses the current technological and regulatory landscape and potential hazards and risks to the environment of nano-enabled medical products, data gaps and gives tentative suggestions relating to possible environmental hotspots. This review paper presents a framework to understand environmental issues relating to nanomedicines and our ability to control such issues.</abstract><cop>England</cop><pmid>24592432</pmid><doi>10.1039/c2em30640a</doi><tpages>22</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2050-7887
ispartof Environmental science--processes & impacts, 2013-01, Vol.15 (1), p.123-144
issn 2050-7887
2050-7895
language eng
recordid cdi_proquest_miscellaneous_1504454140
source MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection
subjects Drug and Narcotic Control
Drug Delivery Systems
Environmental Policy
Environmental Pollutants
Nanoparticles
Pharmaceutical Preparations
Risk Assessment
title Potential environmental implications of nano-enabled medical applications: critical review
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T15%3A23%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Potential%20environmental%20implications%20of%20nano-enabled%20medical%20applications:%20critical%20review&rft.jtitle=Environmental%20science--processes%20&%20impacts&rft.au=Mahapatra,%20Indrani&rft.date=2013-01-01&rft.volume=15&rft.issue=1&rft.spage=123&rft.epage=144&rft.pages=123-144&rft.issn=2050-7887&rft.eissn=2050-7895&rft_id=info:doi/10.1039/c2em30640a&rft_dat=%3Cproquest_cross%3E1504454140%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1504454140&rft_id=info:pmid/24592432&rfr_iscdi=true