Development and in vitro Evaluation of Antigen-Loaded Poly(amidoamine) Nanoparticles for Respiratory Epithelium Applications

A poly(amidoamine) with disulfide linkages in the main chain and 4‐hydroxybutyl and ω‐carboxy‐PEG groups (9:1 ratio) as side chains was prepared by Michael addition polymerization of cystamine bisacrylamide with 4‐hydroxybutylamine and ω‐carboxy‐PEG‐amine. To develop therapeutic protein formulations...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	ChemMedChem 2013-11, Vol.8 (11), p.1787-1794
Hauptverfasser:	Coué, Grégory, Hermanns, Iris, Unger, Ronald E., Kirkpatrick, C. James, Engbersen, Johan F. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal antigens Antigens - chemistry Cells, Cultured Efficiency Humans intranasal delivery Medical research Models, Biological Nanoparticles Nanoparticles - chemistry Particle Size poly(amidoamine) Polyamines - chemistry Polyamines - pharmacology protein delivery Respiratory Mucosa - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!