A closer look at the immediate trabecula response to combined parathyroid hormone and alendronate treatment

Abstract Daily injections of parathyroid hormone (PTH) are the only FDA-approved anabolic treatment for osteoporosis; however PTH is only clinically approved for treatment periods of up to 24 months. To enhance its anabolic effect, combining PTH with anti-resorptive therapy was proposed and expected...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2014-04, Vol.61, p.149-157
Hauptverfasser:	Altman, Allison R, Tseng, Wei-Ju, de Bakker, Chantal M.J, Huh, Beom Kang, Chandra, Abhishek, Qin, Ling, Liu, X. Sherry
Format:	Artikel
Sprache:	eng
Schlagworte:	3D image registration Alendronate - pharmacology Animal models/rodent Animals Anti-resorptive treatment Biological and medical sciences Bone and Bones - drug effects Bone Density - drug effects Bone Density Conservation Agents - pharmacology Bones, joints and connective tissue. Antiinflammatory agents Female Finite Element Analysis Fundamental and applied biological sciences. Psychology In vivo μCT Medical sciences Orthopedics Parathyroid hormone Parathyroid Hormone - pharmacology Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Tomography, X-Ray Computed Trabecular bone microstructure Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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