Performance of direct estradiol immunoassays with human male serum samples

Steroid immunoassays originally required solvent extraction, chromatography, and structurally authentic tracers to avoid interference from steroid cross-reactivity and matrix effects. The demand for steroid assays has driven assay simplification, bypassing this triplet of validity criteria to allow...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2014-03, Vol.60 (3), p.510-517
Hauptverfasser:	Handelsman, David J, Newman, Julie D, Jimenez, Mark, McLachlan, Robert, Sartorius, Gideon, Jones, Graham R D
Format:	Artikel
Sprache:	eng
Schlagworte:	Bias Bone density Chromatography, Liquid - standards Estradiol - blood Estrogens Humans Immunoassay - standards Immunoassays Male Mass Spectrometry - standards Men Mens health Methods Middle Aged Pathology Reference Values Solvent extraction Steroids Womens health
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