Genetic Susceptibility, Dietary Antioxidants, and Long-Term Incidence of Age-Related Macular Degeneration in Two Populations

Objective To examine effect modification between genetic susceptibility to age-related macular degeneration (AMD) and dietary antioxidant or fish consumption on AMD risk. Design Pooled data analysis of population-based cohorts. Participants Participants from the Blue Mountains Eye Study (BMES) and R...

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Veröffentlicht in:	Ophthalmology (Rochester, Minn.) Minn.), 2014-03, Vol.121 (3), p.667-675
Hauptverfasser:	Wang, Jie Jin, MMed, PhD, Buitendijk, Gabriëlle H.S., MD, MSc, Rochtchina, Elena, BSc, MAppStat, Lee, Kristine E., MS, Klein, Barbara E.K., MD, MPH, van Duijn, Cornelia M., PhD, Flood, Victoria M., MPH, PhD, Meuer, Stacy M., BS, Attia, John, MD, PhD, Myers, Chelsea, MStat, Holliday, Elizabeth G., PhD, Tan, Ava G., MAIT, MPH, Smith, Wayne T., MBBS, PhD, Iyengar, Sudha K., PhD, de Jong, Paulus T.V.M., MD, PhD, Hofman, Albert, MD, PhD, Vingerling, Johannes R., MD, PhD, Mitchell, Paul, MD, PhD, Klein, Ronald, MD, MPH, Klaver, Caroline C.W., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants - administration & dosage Ascorbic Acid - administration & dosage beta Carotene - administration & dosage Complement Factor H - genetics Diet Fatty Acids, Omega-3 - administration & dosage Feeding Behavior Female Fish Products Fruit Genetic Predisposition to Disease Genotyping Techniques Humans Incidence Lutein - administration & dosage Macular Degeneration - epidemiology Macular Degeneration - genetics Macular Degeneration - prevention & control Male Middle Aged Molecular Epidemiology Netherlands - epidemiology New South Wales - epidemiology Ophthalmology Proteins - genetics Surveys and Questionnaires Vegetables Xanthophylls - administration & dosage Zeaxanthins Zinc Compounds - administration & dosage
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