Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: In vitro study

Abstract Objective This in vitro study aims to evaluate the effect of low fluoride (F) gel associate sodium trimetaphosphate (TMP) on erosion with or without abrasion. Design Enamel blocks (4 mm × 4 mm) selected through surface hardness (SH) is divided into five groups ( n = 12): gel without F and T...

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Veröffentlicht in:Archives of oral biology 2014-03, Vol.59 (3), p.336-340
Hauptverfasser: Pancote, L.P, Manarelli, M.M, Danelon, M, Delbem, A.C.B
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container_title Archives of oral biology
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creator Pancote, L.P
Manarelli, M.M
Danelon, M
Delbem, A.C.B
description Abstract Objective This in vitro study aims to evaluate the effect of low fluoride (F) gel associate sodium trimetaphosphate (TMP) on erosion with or without abrasion. Design Enamel blocks (4 mm × 4 mm) selected through surface hardness (SH) is divided into five groups ( n = 12): gel without F and TMP (placebo), gel containing 4500 ppm F (4500), gel containing 4500 ppm F plus TMP5% (4500 TMP5%), gel containing 9000 ppm F (9000), and gel containing 12,300 ppm F (acid gel). Those groups were additionally subdivided into conditions of erosion (Ero) and of erosion plus abrasion (Ero/Abra). The blocks have undergone a single application of gel on the first day of the study. The erosion challenge was produced by Sprite Zero® for five minutes four times a day and abrasion was carried out by machine brushing for 15 s. After the challenges, the surface hardness (%SH), wear and cross-sectional hardness (ΔKHN) were analyzed. The data were analyzed using a 2-way ANOVA test followed by a Student-Newman–Keuls ( p < 0.05). Results Lower values of %SH, wear and ΔKHN were observed for erosion challenge ( p < 0.001). The %SH was lower in groups treated with fluoride gels, differing in the placebo ( p < 0.05). With addition of TMP to the gel 4500, enamel wear was lower when compared with another groups ( p < 0.05). Conclusion In vitro conditions, the 4500 5%TMP gel showed greatest effect against erosion and erosion/abrasion.
doi_str_mv 10.1016/j.archoralbio.2013.12.007
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Design Enamel blocks (4 mm × 4 mm) selected through surface hardness (SH) is divided into five groups ( n = 12): gel without F and TMP (placebo), gel containing 4500 ppm F (4500), gel containing 4500 ppm F plus TMP5% (4500 TMP5%), gel containing 9000 ppm F (9000), and gel containing 12,300 ppm F (acid gel). Those groups were additionally subdivided into conditions of erosion (Ero) and of erosion plus abrasion (Ero/Abra). The blocks have undergone a single application of gel on the first day of the study. The erosion challenge was produced by Sprite Zero® for five minutes four times a day and abrasion was carried out by machine brushing for 15 s. After the challenges, the surface hardness (%SH), wear and cross-sectional hardness (ΔKHN) were analyzed. The data were analyzed using a 2-way ANOVA test followed by a Student-Newman–Keuls ( p &lt; 0.05). Results Lower values of %SH, wear and ΔKHN were observed for erosion challenge ( p &lt; 0.001). The %SH was lower in groups treated with fluoride gels, differing in the placebo ( p &lt; 0.05). With addition of TMP to the gel 4500, enamel wear was lower when compared with another groups ( p &lt; 0.05). Conclusion In vitro conditions, the 4500 5%TMP gel showed greatest effect against erosion and erosion/abrasion.</description><identifier>ISSN: 0003-9969</identifier><identifier>EISSN: 1879-1506</identifier><identifier>DOI: 10.1016/j.archoralbio.2013.12.007</identifier><identifier>PMID: 24581857</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Advanced Basic Science ; Animals ; Cariostatic Agents - pharmacology ; Cattle ; Dental enamel ; Dental Enamel - drug effects ; Dentistry ; Fluoride gels ; Fluorides, Topical - pharmacology ; Gels ; Hardness ; Hydrogen-Ion Concentration ; In Vitro Techniques ; Polyphosphates ; Polyphosphates - pharmacology ; Surface Properties ; Tooth abrasion ; Tooth Abrasion - prevention &amp; control ; Tooth erosion ; Tooth Erosion - prevention &amp; control ; Topical fluorides</subject><ispartof>Archives of oral biology, 2014-03, Vol.59 (3), p.336-340</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>Copyright © 2013 Elsevier Ltd. 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Design Enamel blocks (4 mm × 4 mm) selected through surface hardness (SH) is divided into five groups ( n = 12): gel without F and TMP (placebo), gel containing 4500 ppm F (4500), gel containing 4500 ppm F plus TMP5% (4500 TMP5%), gel containing 9000 ppm F (9000), and gel containing 12,300 ppm F (acid gel). Those groups were additionally subdivided into conditions of erosion (Ero) and of erosion plus abrasion (Ero/Abra). The blocks have undergone a single application of gel on the first day of the study. The erosion challenge was produced by Sprite Zero® for five minutes four times a day and abrasion was carried out by machine brushing for 15 s. After the challenges, the surface hardness (%SH), wear and cross-sectional hardness (ΔKHN) were analyzed. The data were analyzed using a 2-way ANOVA test followed by a Student-Newman–Keuls ( p &lt; 0.05). Results Lower values of %SH, wear and ΔKHN were observed for erosion challenge ( p &lt; 0.001). The %SH was lower in groups treated with fluoride gels, differing in the placebo ( p &lt; 0.05). With addition of TMP to the gel 4500, enamel wear was lower when compared with another groups ( p &lt; 0.05). 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Design Enamel blocks (4 mm × 4 mm) selected through surface hardness (SH) is divided into five groups ( n = 12): gel without F and TMP (placebo), gel containing 4500 ppm F (4500), gel containing 4500 ppm F plus TMP5% (4500 TMP5%), gel containing 9000 ppm F (9000), and gel containing 12,300 ppm F (acid gel). Those groups were additionally subdivided into conditions of erosion (Ero) and of erosion plus abrasion (Ero/Abra). The blocks have undergone a single application of gel on the first day of the study. The erosion challenge was produced by Sprite Zero® for five minutes four times a day and abrasion was carried out by machine brushing for 15 s. After the challenges, the surface hardness (%SH), wear and cross-sectional hardness (ΔKHN) were analyzed. The data were analyzed using a 2-way ANOVA test followed by a Student-Newman–Keuls ( p &lt; 0.05). Results Lower values of %SH, wear and ΔKHN were observed for erosion challenge ( p &lt; 0.001). The %SH was lower in groups treated with fluoride gels, differing in the placebo ( p &lt; 0.05). With addition of TMP to the gel 4500, enamel wear was lower when compared with another groups ( p &lt; 0.05). Conclusion In vitro conditions, the 4500 5%TMP gel showed greatest effect against erosion and erosion/abrasion.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>24581857</pmid><doi>10.1016/j.archoralbio.2013.12.007</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-8159-4853</orcidid></addata></record>
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subjects Advanced Basic Science
Animals
Cariostatic Agents - pharmacology
Cattle
Dental enamel
Dental Enamel - drug effects
Dentistry
Fluoride gels
Fluorides, Topical - pharmacology
Gels
Hardness
Hydrogen-Ion Concentration
In Vitro Techniques
Polyphosphates
Polyphosphates - pharmacology
Surface Properties
Tooth abrasion
Tooth Abrasion - prevention & control
Tooth erosion
Tooth Erosion - prevention & control
Topical fluorides
title Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: In vitro study
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