Detection of miR-34a and miR-34b/c in stool sample as potential screening biomarkers for noninvasive diagnosis of colorectal cancer

Explore potential screening biomarkers for noninvasive diagnosis of colorectal cancer (CRC) by testing methylation of the miR-34a and miR-34b/c promoter in CRC patients’ tissue and stool samples. Methylation-specific PCR analyses were performed on sample DNAs: 82 pairs of normal/cancer samples, 82 C...

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Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2014-04, Vol.31 (4), p.894-894, Article 894
Hauptverfasser:	Wu, Xuan-di, Song, Yong-Chun, Cao, Pei-Long, Zhang, Hao, Guo, Qi, Yan, Rong, Diao, Dong-mei, Cheng, Yao, Dang, Cheng-Xue
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - metabolism Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism DNA Methylation Feces Female Gene Expression Regulation, Neoplastic Healthy Volunteers Hematology Humans Internal Medicine Lymphatic Metastasis Male Medicine Medicine & Public Health MicroRNAs - metabolism Middle Aged Oncology Original Paper Pathology Polymerase Chain Reaction Sensitivity and Specificity Sequence Analysis, DNA
Online-Zugang:	Volltext
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