Does omethoate have the potential to cause insulin resistance?

Highlights • Omethoate exposure caused oxidative stress in rats exposed to omethoate. • TNF-α and IL-6 levels were increased in skeletal muscles of omethoate exposed rats. • JNK and p38MAPK were activated in the skeletal muscles of omethoate exposed rats. • NF-κB was also activated in the skeletal m...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2014-01, Vol.37 (1), p.284-290
Hauptverfasser:	Zhang, Yunjian, Ren, Ming, Li, Jianhui, Wei, Qian, Ren, Zhixing, Lv, Jingmao, Niu, Fenglan, Ren, Shuping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - analysis Dimethoate - analogs & derivatives Dimethoate - toxicity Emergency Glutathione Peroxidase - metabolism IL-6 Insecticides - toxicity Insulin - blood Insulin Resistance Interleukin-6 - blood JNK JNK Mitogen-Activated Protein Kinases - metabolism Male Malondialdehyde - metabolism Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism NF-kappa B - metabolism NF-κB Omethoate p38 Mitogen-Activated Protein Kinases - metabolism Rats Rats, Wistar Superoxide Dismutase - metabolism TNF-α Tumor Necrosis Factor-alpha - blood
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