Identification and Characterization of a Mitogen-Activated S6 Kinase

Treatment of Swiss mouse 3T3 cells with epidermal growth factor, orthovanadate, or serum results in the activation of a kinase that phosphorylates protein S6 of the 40S ribosomal subunit in vitro. This kinase is eluted as a single peak of activity from either a Mono Q anion-exchange column at 0.34 M...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1988-01, Vol.85 (2), p.406-410
Hauptverfasser:	Jenö, Paul, Ballou, Lisa M., Novak-Hofer, Ilse, Thomas, George
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 cells Analytical, structural and metabolic biochemistry Animals Biological and medical sciences cell culture Cell extracts Cells, Cultured Enzyme Activation Enzymes Enzymes and enzyme inhibitors Epidermal Growth Factor - pharmacology Fundamental and applied biological sciences. Psychology Gels Kinetics Mice Mitogens Molecular Weight orthovanadate Phosphatases Phosphates Phosphorylation Protein Kinases - isolation & purification Protein Kinases - metabolism protein phosphatase 2A Ribosomal Protein S6 Kinases ribosomal proteins S6 kinase Transferases Vanadates Vanadates - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!