Characterization of seizure-like events recorded in vivo in a mouse model of Rett syndrome

Rett syndrome is a neurodevelopmental disorder caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MECP2). Spontaneous recurrent discharge episodes are displayed in Rett-related seizures as in other types of epilepsies. The aim of this paper is to investigate the seizure-...

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Veröffentlicht in:	Neural networks 2013-10, Vol.46, p.109-115
Hauptverfasser:	Colic, Sinisa, Wither, Robert G., Zhang, Liang, Eubanks, James H., Bardakjian, Berj L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Automated seizure detection Biological and medical sciences Disease Models, Animal Epilepsy Female Gamma distribution Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Medical sciences Methyl-CpG-Binding Protein 2 - deficiency Methyl-CpG-Binding Protein 2 - genetics Mice Mutation - genetics Nervous system (semeiology, syndromes) Neurology Phenotype Rett syndrome Rett Syndrome - genetics Rett Syndrome - metabolism Rett Syndrome - physiopathology Seizure Seizures - physiopathology
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