Amphetamine dephosphorylates ERM proteins in the nucleus accumbens core and lithium attenuates its effects

•The first study examining the role of amphetamine in ERM regulation in the brain.•Amphetamine decreases ERM phosphorylation in the nucleus accumbens core.•Lithium recovers decrease of ERM phosphorylation in this site. The ezrin–radixin–moesin (ERM) proteins have been implicated not only in cell-sha...

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Veröffentlicht in:	Neuroscience letters 2013-09, Vol.552, p.103-107
Hauptverfasser:	Kim, Wha Young, Jang, Ju Kyong, Shin, Joong-Keun, Kim, Jeong-Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphetamine Animals Antimanic Agents - pharmacology Central Nervous System Stimulants - antagonists & inhibitors Central Nervous System Stimulants - pharmacology Cytoskeletal Proteins - metabolism Dextroamphetamine - antagonists & inhibitors Dextroamphetamine - pharmacology ERM Lithium Lithium Chloride - pharmacology Male Membrane Proteins - metabolism Microfilament Proteins - metabolism Nucleus accumbens Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Phosphorylation - drug effects Rats
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