GABAergic activity in autism spectrum disorders: An investigation of cortical inhibition via transcranial magnetic stimulation

Mounting evidence suggests a possible role for γ-aminobutyric acid (GABA) in the neuropathophysiology of autism spectrum disorders (ASD), but the extent of this impairment is unclear. A non-invasive, in vivo measure of GABA involves transcranial magnetic stimulation (TMS) of the primary motor cortex...

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Veröffentlicht in:	Neuropharmacology 2013-05, Vol.68, p.202-209
Hauptverfasser:	Enticott, Peter G., Kennedy, Hayley A., Rinehart, Nicole J., Tonge, Bruce J., Bradshaw, John L., Fitzgerald, Paul B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Asperger Syndrome - metabolism Asperger Syndrome - physiopathology Asperger's disorder Autism Autistic disorder Autistic Disorder - metabolism Autistic Disorder - physiopathology Electromyography Evoked Potentials, Motor - physiology Female GABA gamma-Aminobutyric Acid - metabolism Humans Male Motor Cortex - metabolism Motor Cortex - physiopathology Neural Inhibition - physiology Primary motor cortex Transcranial Magnetic Stimulation
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