Polysaccharide-based nucleic acid nanoformulations

Therapeutic application of nucleic acids requires their encapsulation in nanosized carriers that enable safe and efficient intracellular delivery. Before the desired site of action is reached, drug-loaded nanoparticles (nanomedicines) encounter numerous extra- and intracellular barriers. Judicious n...

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Veröffentlicht in:	Advanced drug delivery reviews 2013-08, Vol.65 (9), p.1123-1147
Hauptverfasser:	Raemdonck, Koen, Martens, Thomas F., Braeckmans, Kevin, Demeester, Jo, De Smedt, Stefaan C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemistry, Pharmaceutical Chitosan Cyclodextrin Dextran Drug Carriers - chemistry Gene therapy Humans Hyaluronic acid Nanomedicine Nanoparticles - chemistry Nucleic Acids - chemistry Plasmid DNA Polysaccharides - chemistry siRNA
Online-Zugang:	Volltext
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