Raman spectroscopy to distinguish grey matter, necrosis, and glioblastoma multiforme in frozen tissue sections

The need exists for a highly accurate, efficient and inexpensive tool to distinguish normal brain tissue from glioblastoma multiforme (GBM) and necrosis boundaries rapidly, in real-time, in the operating room. Raman spectroscopy provides a unique biochemical signature of a tissue type, with the pote...

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Veröffentlicht in:	Journal of neuro-oncology 2014-02, Vol.116 (3), p.477-485
Hauptverfasser:	Kalkanis, Steven N., Kast, Rachel E., Rosenblum, Mark L., Mikkelsen, Tom, Yurgelevic, Sally M., Nelson, Katrina M., Raghunathan, Aditya, Poisson, Laila M., Auner, Gregory W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Boundaries Brain - pathology Brain Mapping Brain Neoplasms - pathology Discriminant Analysis Female Frozen Sections Glioblastoma - pathology Humans Laboratory Investigation Male Medicine Medicine & Public Health Middle Aged Necrosis - pathology Neurology Oncology Spectrum Analysis, Raman Time Factors
Online-Zugang:	Volltext
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