SPIO nanoparticle-stabilized PAA-F127 thermosensitive nanobubbles with MR/US dual-modality imaging and HIFU-triggered drug release for magnetically guided in vivo tumor therapy

Nanobubbles can serve as promising, next-generation theranostic platforms for ultrasound (US) and magnetic resonance (MR) imaging, and combined magnetic targeting (MT) and high-intensity focused ultrasound (HIFU)-triggered drug release for tumor therapy. Nanobubble-based dual contrast enhancement ag...

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Veröffentlicht in:	Journal of controlled release 2013-11, Vol.172 (1), p.118-127
Hauptverfasser:	Huang, Hsin-Yang, Hu, Shang-Hsiu, Hung, Shih-Ya, Chiang, Chih-Sheng, Liu, Hao-Li, Chiu, Tsung-Lang, Lai, Hsin-Yi, Chen, You-Yin, Chen, San-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins - chemistry Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - therapeutic use Cancer Contrast Media - chemistry Drug Delivery Systems - methods drug therapy drugs emulsions Female Focus ultrasound image analysis iron oxides Magnetic Resonance Imaging - methods Magnetic targeting Magnetite Nanoparticles - chemistry Magnetite Nanoparticles - ultrastructure Mice Mice, Nude Microbubbles Models, Molecular Nanobubble nanoparticles neoplasms Neoplasms - diagnosis Neoplasms - drug therapy permeability polyacrylic acid Polyethylenes - chemistry Polypropylenes - chemistry Rats Rats, Wistar Superparamagnetic ultrasonics Ultrasonics - methods
Online-Zugang:	Volltext
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