CT imaging of myocardial scars with collagen-targeting gold nanoparticles

Abstract In the setting of myocardial ischemia, recovery of myocardial function by revascularization procedures depends on the extent of coronary disease and myocardial scar burden. Currently, computed tomographic (CT) imaging offers superior evaluation of coronary lesions but lacks the capability t...

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Veröffentlicht in:	Nanomedicine 2013-10, Vol.9 (7), p.1067-1076
Hauptverfasser:	Danila, Delia, PhD, Johnson, Evan, MS, Kee, Patrick, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins Animals Cicatrix - diagnostic imaging Cicatrix - pathology Collagen - metabolism Collagen - pharmacokinetics CT imaging Female Gold - metabolism Gold - pharmacokinetics Gold nanoparticles Internal Medicine Light Metal Nanoparticles Mice Mice, Inbred C57BL Molecular imaging Myocardial Infarction - diagnostic imaging Myocardial Infarction - pathology Myocardial scars Myocardium - pathology Polyethylene Glycols - chemistry Protein Binding Scattering, Radiation Tissue Distribution Tomography, X-Ray Computed
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