White matter microstructural damage in Alzheimer's disease at different ages of onset

Abstract White matter (WM) microstructural damage and its relationship with cortical abnormalities were explored in early-onset Alzheimer's disease (EOAD) compared with late-onset AD (LOAD) patients. Structural and diffusion tensor magnetic resonance images were obtained from 22 EOAD patients,...

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Veröffentlicht in:	Neurobiology of aging 2013-10, Vol.34 (10), p.2331-2340
Hauptverfasser:	Canu, Elisa, Agosta, Federica, Spinelli, Edoardo G, Magnani, Giuseppe, Marcone, Alessandra, Scola, Elisa, Falautano, Monica, Comi, Giancarlo, Falini, Andrea, Filippi, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age of Onset Aged Aged, 80 and over Alzheimer Disease - epidemiology Alzheimer Disease - pathology Brain Mapping Cerebral Cortex - pathology Corpus Callosum - pathology Diffusion Magnetic Resonance Imaging - methods Diffusion Tensor Imaging Diffusion tensor MRI Early-onset Alzheimer's disease Female Gyrus Cinguli - pathology Humans Internal Medicine Late-onset Alzheimer's disease Male Middle Aged MRI Neurology Severity of Illness Index White matter damage
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