Functional analysis of domain of unknown function (DUF) 1943, DUF1944 and von Willebrand factor type D domain (VWD) in vitellogenin2 in zebrafish

•Both rDUF1943 and rDUF1944 as well as rVWD were able to bind to Gram-positive and negative bacteria.•Both rDUF1943 and rDUF1944 as well as rVWD showed affinity to LTA and LPS.•Both rDUF1943 and rDUF1944 enhanced phagocytosis of bacteria by macrophages.•This opens a new angle for identification of g...

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Veröffentlicht in:Developmental and comparative immunology 2013-12, Vol.41 (4), p.469-476
Hauptverfasser: Sun, Chen, Hu, Lili, Liu, Shousheng, Gao, Zhan, Zhang, Shicui
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Sprache:eng
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