Behavioural and neurochemical comparison of chronic intermittent cathinone, mephedrone and MDMA administration to the rat

Abstract The synthetic cathinone derivative, mephedrone, is a controlled substance across Europe. Its effects have been compared by users to 3,4-methylenedioxymethamphetamine (MDMA), but little data exist on its pharmacological properties. This study compared the behavioural and neurochemical effect...

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Veröffentlicht in:	European neuropsychopharmacology 2013-09, Vol.23 (9), p.1085-1095
Hauptverfasser:	Shortall, Sinead E, Macerola, Alice E, Swaby, Rabbi T.R, Jayson, Rebecca, Korsah, Chantal, Pillidge, Katharine E, Wigmore, Peter M, Ebling, Francis J.P, Richard Green, A, Fone, Kevin C.F, King, Madeleine V
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT Acoustic startle response Alkaloids - administration & dosage Animals Brain - drug effects Brain - metabolism Cathinone Conditioning (Psychology) - drug effects Conditioning (Psychology) - physiology Dopamine Dose-Response Relationship, Drug Drug Administration Schedule Internal Medicine Locomotion Male MDMA Mephedrone Methamphetamine - administration & dosage Methamphetamine - analogs & derivatives Motor Activity - drug effects Motor Activity - physiology N-Methyl-3,4-methylenedioxyamphetamine - administration & dosage Psychiatry Random Allocation Rats
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