Repetitive domestication to enhance butanol tolerance and production in Clostridium acetobutylicum through artificial simulation of bio-evolution

► A novel approach was developed on the basis of dynamics of evolution and selection. ► A butanol-tolerant strain with increased butanol tolerance was obtained. ► Artificial simulation of bio-evolution (ASBE) was employed in biotechnology. ► The efficiency of ASBE was evaluated. ► The relationship b...

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Veröffentlicht in:	Bioresource technology 2013-02, Vol.130, p.638-643
Hauptverfasser:	Liu, Xiao-Bo, Gu, Qiu-Ya, Yu, Xiao-Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	ABE production Biofuel Biofuel production Biofuels Biological and medical sciences Biological Evolution Biotechnology Butanol Butanol tolerance Butanols - toxicity Cell Proliferation Clostridium acetobutylicum Clostridium acetobutylicum - cytology Clostridium acetobutylicum - drug effects Clostridium acetobutylicum - genetics Corn Domestication Dynamic tests Energy Evolutionary Fundamental and applied biological sciences. Psychology Industrial applications and implications. Economical aspects Kinetics Selection, Genetic Simulation Tolerances
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