Expression of Programmed Death-1 (PD-1) on CD4+ and CD8+ T cells in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by chronic inflammatory process that targets the synovial lining of diarthrodial joints. Programmed death 1 (PD-1) plays a key role in the negative regulation of the immune response. In the current study, we investigated the expression of PD-1 on peripheral...

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Veröffentlicht in:	Inflammation 2014-02, Vol.37 (1), p.116-121
Hauptverfasser:	Li, Shufeng, Liao, Wensheng, Chen, Meng, Shan, Shiying, Song, Yuanlin, Zhang, Shuzhen, Song, Haihan, Yuan, Zhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - pathology Biomedicine C-reactive protein C-Reactive Protein - metabolism CD4 antigen CD4-Positive T-Lymphocytes - immunology CD8 antigen CD8-Positive T-Lymphocytes - immunology Down-Regulation Female Flow cytometry Humans Immunology Inflammation Inflammation - immunology Internal Medicine Joint diseases Lymphocytes Lymphocytes T Male Middle Aged Pathology Patients PD-1 protein Pharmacology/Toxicology Programmed Cell Death 1 Receptor - biosynthesis Programmed Cell Death 1 Receptor - blood Rheumatoid arthritis Rheumatology Serum levels Synovial Membrane - pathology
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