Extended-release naltrexone (XR-NTX) attenuates brain responses to alcohol cues in alcohol-dependent volunteers: A bold FMRI study

Oral naltrexone reduces heavy drinking, but is less consistent as an abstinence promoter, whereas once-monthly extended-release naltrexone (XR-NTX) also maintains abstinence. The present study sought to determine if alcohol cue reactivity is attenuated by XR-NTX. Twenty-eight detoxified alcohol-depe...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2013-09, Vol.78, p.176-185
Hauptverfasser:	Lukas, Scott E., Lowen, Steven B., Lindsey, Kimberly P., Conn, Nina, Tartarini, Wendy, Rodolico, John, Mallya, Gopi, Palmer, Christopher, Penetar, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adult Adult and adolescent clinical studies Alcohol Alcoholism Alcoholism - drug therapy Alcoholism - physiopathology Alcoholism and acute alcohol poisoning Biological and medical sciences Brain Brain - drug effects Brain - physiopathology Brain Mapping Craving Cues Delayed-Action Preparations Double-Blind Method Female fMRI Humans Magnetic Resonance Imaging Male Medical sciences Middle Aged Naltrexone Naltrexone - administration & dosage Narcotic Antagonists - administration & dosage Nervous system Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Toxicology Volunteers
Online-Zugang:	Volltext
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