1,2,3-Triazole-derived naphthalimides as a novel type of potential antimicrobial agents: synthesis, antimicrobial activity, interaction with calf thymus DNA and human serum albumin

A series of 1,2,3-triazole-derived naphthalimides as a novel type of potential antimicrobial agents were synthesized and characterized by IR, NMR and HRMS spectra. All the new compounds were screened for their antimicrobial activity against four Gram-positive bacteria, four Gram-negative bacteria an...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2014-01, Vol.24 (1), p.308-313
Hauptverfasser:	Lv, Jing-Song, Peng, Xin-Mei, Kishore, Baathulaa, Zhou, Cheng-He
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Bacteria - drug effects Cattle DNA - chemistry DNA - metabolism DNA Replication - drug effects Dose-Response Relationship, Drug Humans Microbial Sensitivity Tests Molecular Structure Naphthalimides - chemical synthesis Naphthalimides - chemistry Naphthalimides - pharmacology Serum Albumin - chemistry Serum Albumin - metabolism Static Electricity Structure-Activity Relationship Triazoles - chemistry
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