Systematic review and meta-analysis of cytokeratin 19-based one-step nucleic acid amplification versus histopathology for sentinel lymph node assessment in breast cancer

Background One‐step nucleic acid amplification (OSNA) is a new rapid assay for detecting breast cancer metastases during surgery, saving a second procedure for patients requiring an axillary clearance. Many centres in the UK and abroad have adopted OSNA in place of routine histopathology, despite no...

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Veröffentlicht in:	British journal of surgery 2014-03, Vol.101 (4), p.298-306
Hauptverfasser:	Tiernan, J. P., Verghese, E. T., Nair, A., Pathak, S., Kim, B., White, J., Thygesen, H., Horgan, K., Hanby, A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - diagnosis Female Humans Intraoperative Care - methods Keratin-19 - genetics Keratin-19 - metabolism Lymph Nodes - pathology Lymphatic Metastasis Nucleic Acid Amplification Techniques - methods Nucleic Acid Amplification Techniques - standards Sensitivity and Specificity Sentinel Lymph Node Biopsy - methods Sentinel Lymph Node Biopsy - standards
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