Dissecting the evolutionary stealth of our flora against antibiotics

It is one thing to have an organism develop resistance to an agent to which it is exposed. But organisms are even 'smarter' as they stealthily evade our surveillance as subtle but relevant resistance genes sneak into our 'normal flora'. Transmissible quinolone resistance and ...

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Veröffentlicht in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2014-03, Vol.108 (3), p.121-122, Article 121
Hauptverfasser: Mathers, Amy J., Guerrant, Richard L.
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container_title Transactions of the Royal Society of Tropical Medicine and Hygiene
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creator Mathers, Amy J.
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description It is one thing to have an organism develop resistance to an agent to which it is exposed. But organisms are even 'smarter' as they stealthily evade our surveillance as subtle but relevant resistance genes sneak into our 'normal flora'. Transmissible quinolone resistance and 'creeping' nalR and cipR mechanisms of moderate, but incremental, marches toward resistance are becoming common in the commensal flora of human populations under antibiotic pressure.
doi_str_mv 10.1093/trstmh/tru002
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source MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection
subjects Anti-Bacterial Agents - therapeutic use
Drug Resistance, Bacterial - genetics
Genes, Bacterial - genetics
Humans
title Dissecting the evolutionary stealth of our flora against antibiotics
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