Enhanced osteogenic differentiation of MC3T3-E1 on rhBMP-2-immobilized titanium via click reaction

•Click chemistry is a good method to conjugate BMP-2 on Ti surface.•BMP-2 well-controllably released for 28 days.•Ti-6 was a useful tool to enhance the osteogenesis of MC3T3-E1. In the present study, we report about the efficacy of titanium surface-immobilized with bone morphogenetic protein-2 (BMP-...

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Veröffentlicht in:	Carbohydrate polymers 2014-03, Vol.103, p.170-178
Hauptverfasser:	Kim, Eun-Cheol, Kim, Tae-Hee, Jung, Jae-Hoon, Hong, Sung Ok, Lee, Deok-Won
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Biological and medical sciences Biotechnology BMP-2 Bone Morphogenetic Protein 2 - chemistry Cell Differentiation - drug effects Cell Proliferation - drug effects Cells, Cultured Click Chemistry Fundamental and applied biological sciences. Psychology Immobilization of enzymes and other molecules Immobilization techniques MC3T3-E1 cell Methods. Procedures. Technologies Mice Osteogenesis - drug effects Osteogenic differentiation Recombinant Proteins - chemistry Structure-Activity Relationship Surface Properties Titanium - chemistry Titanium - pharmacology Titanium surface
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