A chromosome study of three ovarian tumors
The cytogenetic results of three different types of malignant ovarian tumors are reported. Their chromosomes were studied indirectly by using either peritoneal washings or ascitic fluids. Detected in the peritoneal washings from a treated case of serous cystadenocarcinoma with papillary involvement,...
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| Veröffentlicht in: | Cancer genetics and cytogenetics 1987, Vol.26 (2), p.327-337 |
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| container_end_page | 337 |
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| container_title | Cancer genetics and cytogenetics |
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| creator | Jenkyn, D.J. McCartney, A.J. |
| description | The cytogenetic results of three different types of malignant ovarian tumors are reported. Their chromosomes were studied indirectly by using either peritoneal washings or ascitic fluids. Detected in the peritoneal washings from a treated case of serous cystadenocarcinoma with papillary involvement, stage III, was a clone of pseudodiploid cells. They were found after 12 months of chemotherapy. No supporting evidence of malignancy was found cytologically. Relatively simple karyotypes were obtained from metaphases found in the ascitic fluid of a patient surgically treated for an immature teratoma, stage II, grade 3. Consistent abnormalities found were trisomy 2, del(3)(p14), and der(5)t(5;8)(q33;q11). Of prime interest in a case of dysgerminoma, stage IV, was the finding of the isochromosome i(12p), a recognized nonrandom abnormality of malignant testicular tumors [1–5]. |
| doi_str_mv | 10.1016/0165-4608(87)90067-7 |
| format | Article |
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Their chromosomes were studied indirectly by using either peritoneal washings or ascitic fluids. Detected in the peritoneal washings from a treated case of serous cystadenocarcinoma with papillary involvement, stage III, was a clone of pseudodiploid cells. They were found after 12 months of chemotherapy. No supporting evidence of malignancy was found cytologically. Relatively simple karyotypes were obtained from metaphases found in the ascitic fluid of a patient surgically treated for an immature teratoma, stage II, grade 3. Consistent abnormalities found were trisomy 2, del(3)(p14), and der(5)t(5;8)(q33;q11). 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Their chromosomes were studied indirectly by using either peritoneal washings or ascitic fluids. Detected in the peritoneal washings from a treated case of serous cystadenocarcinoma with papillary involvement, stage III, was a clone of pseudodiploid cells. They were found after 12 months of chemotherapy. No supporting evidence of malignancy was found cytologically. Relatively simple karyotypes were obtained from metaphases found in the ascitic fluid of a patient surgically treated for an immature teratoma, stage II, grade 3. Consistent abnormalities found were trisomy 2, del(3)(p14), and der(5)t(5;8)(q33;q11). Of prime interest in a case of dysgerminoma, stage IV, was the finding of the isochromosome i(12p), a recognized nonrandom abnormality of malignant testicular tumors [1–5].</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Chromosome Aberrations</subject><subject>Chromosome Banding</subject><subject>Cystadenocarcinoma - genetics</subject><subject>Dysgerminoma - genetics</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Genetic Markers</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Karyotyping</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Ovarian Neoplasms - genetics</subject><subject>Teratoma - genetics</subject><subject>Tumors</subject><issn>0165-4608</issn><issn>1873-4456</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LxDAQxYMo67r6DRR6EFGhmqRtkl6EZfEfLHjRc0iTCRtpmzVpF_bb23XLHj0MM_B-M8x7CF0S_EAwYY9DFWnOsLgV_K7EmPGUH6EpETxL87xgx2h6QE7RWYzfGGNOSzZBkyznJCN0iu7niV4F3_joG0hi15tt4m3SrQJA4jcqONUmXd_4EM_RiVV1hIuxz9DXy_Pn4i1dfry-L-bLVGeMdCnljFIwpRkGMFQQalRldIULnAlSUFFWAEQZTEmlLc-EIFZYA8yCJoyZbIZu9nfXwf_0EDvZuKihrlULvo-S5GXJSc4GMN-DOvgYA1i5Dq5RYSsJlruI5M6_3PmXgsu_iCQf1q7G-33VgDksjZkM-vWoq6hVbYNqtYsHjOdlwQYvM_S0x2DIYuMgyKgdtBqMC6A7abz7_49fogGBHA</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>Jenkyn, D.J.</creator><creator>McCartney, A.J.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>1987</creationdate><title>A chromosome study of three ovarian tumors</title><author>Jenkyn, D.J. ; McCartney, A.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-27622ed9d276ed2812dabdcb0503815289bee1ad021bcf73881f8fde6fec166d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Chromosome Aberrations</topic><topic>Chromosome Banding</topic><topic>Cystadenocarcinoma - genetics</topic><topic>Dysgerminoma - genetics</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Genetic Markers</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Karyotyping</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Ovarian Neoplasms - genetics</topic><topic>Teratoma - genetics</topic><topic>Tumors</topic><toplevel>online_resources</toplevel><creatorcontrib>Jenkyn, D.J.</creatorcontrib><creatorcontrib>McCartney, A.J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Cancer genetics and cytogenetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jenkyn, D.J.</au><au>McCartney, A.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A chromosome study of three ovarian tumors</atitle><jtitle>Cancer genetics and cytogenetics</jtitle><addtitle>Cancer Genet Cytogenet</addtitle><date>1987</date><risdate>1987</risdate><volume>26</volume><issue>2</issue><spage>327</spage><epage>337</epage><pages>327-337</pages><issn>0165-4608</issn><eissn>1873-4456</eissn><coden>CGCYDF</coden><abstract>The cytogenetic results of three different types of malignant ovarian tumors are reported. Their chromosomes were studied indirectly by using either peritoneal washings or ascitic fluids. Detected in the peritoneal washings from a treated case of serous cystadenocarcinoma with papillary involvement, stage III, was a clone of pseudodiploid cells. They were found after 12 months of chemotherapy. No supporting evidence of malignancy was found cytologically. Relatively simple karyotypes were obtained from metaphases found in the ascitic fluid of a patient surgically treated for an immature teratoma, stage II, grade 3. Consistent abnormalities found were trisomy 2, del(3)(p14), and der(5)t(5;8)(q33;q11). Of prime interest in a case of dysgerminoma, stage IV, was the finding of the isochromosome i(12p), a recognized nonrandom abnormality of malignant testicular tumors [1–5].</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3471312</pmid><doi>10.1016/0165-4608(87)90067-7</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0165-4608 |
| ispartof | Cancer genetics and cytogenetics, 1987, Vol.26 (2), p.327-337 |
| issn | 0165-4608 1873-4456 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Biological and medical sciences Chromosome Aberrations Chromosome Banding Cystadenocarcinoma - genetics Dysgerminoma - genetics Female Female genital diseases Genetic Markers Gynecology. Andrology. Obstetrics Humans Karyotyping Medical sciences Middle Aged Ovarian Neoplasms - genetics Teratoma - genetics Tumors |
| title | A chromosome study of three ovarian tumors |
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