Towards evidence-based dosing regimens in children on the basis of population pharmacokinetic pharmacodynamic modelling

When growing up, the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of drugs change, which may alter the effect of drugs. To ensure optimal drug efficacy and safety in paediatric care, PK and PD relationships of drugs need to be explored in children. This article presents an outline on perfo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of disease in childhood 2014-03, Vol.99 (3), p.267-272
Hauptverfasser:	Admiraal, Rick, van Kesteren, Charlotte, Boelens, Jaap Jan, Bredius, Robbert G M, Tibboel, Dick, Knibbe, Catherijne A J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylating Agents - administration & dosage Alkylating Agents - pharmacokinetics Amikacin - administration & dosage Amikacin - pharmacokinetics Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacokinetics Anti-Bacterial Agents - pharmacokinetics Biological and medical sciences Body Composition Body Weight Busulfan - administration & dosage Busulfan - pharmacokinetics Child Company business management Dose-Response Relationship, Drug Evidence Evidence-Based Medicine General aspects Health aspects Humans Infant health services Management Medical sciences Miscellaneous Models, Biological Morphine - administration & dosage Morphine - pharmacokinetics Narcotics Neonates Patients Pediatrics Pharmacokinetics Pharmacology Prevention and actions Profiles Public health. Hygiene Public health. Hygiene-occupational medicine Sampling Statistical Analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!