The evolution of vancomycin intermediate Staphylococcus aureus (VISA) and heterogenous-VISA

•We review current understanding VISA and hVISA genetics.•We review factors promoting evolution of VISA and loss of resistance phenotype.•We review virulence and other impacts of hVISA and VISA. Resistance to new antimicrobials is generally recognized in Staphylococcus aureus soon after they are rel...

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Veröffentlicht in:	Infection, genetics and evolution genetics and evolution, 2014-01, Vol.21, p.575-582
Hauptverfasser:	Howden, Benjamin P., Peleg, Anton Y., Stinear, Timothy P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Evolution Evolution, Molecular Genetic Variation Genome, Bacterial High-Throughput Nucleotide Sequencing Humans hVISA Phenotype Staphylococcal Infections - epidemiology Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - genetics Vancomycin Resistance Virulence Factors - genetics Virulence Factors - metabolism VISA
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