A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study

To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without clinical cardiovascular disease or significant cardiovascular risk factors, from m...

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Veröffentlicht in:European heart journal cardiovascular imaging 2014-03, Vol.15 (3), p.341-348
Hauptverfasser: Doughty, R. N., Gardin, J. M., Hobbs, F. D. R., McMurray, J. J. V., Nagueh, S. F., Poppe, K. K., Senior, R., Thomas, L., Whalley, G. A., Aune, E., Brown, A., Badano, L. P., Cameron, V., Chadha, D. S., Chahal, N., Chien, K. L., Daimon, M., Dalen, H., Detrano, R., Akif Duzenli, M., Ezekowitz, J., de Simone, G., Di Pasquale, P., Fukuda, S., Gill, P. S., Grossman, E., Kim, H. - K., Kuznetsova, T., Leung, N. K. W., Linhart, A., McDonagh, T. A., McGrady, M., Mill, J. G., Mogelvang, R., Muiesan, M. L., Ng, A. C. T., Ojji, D., Otterstad, J. E., Petrovic, D. J., Prendergast, B., Rietzschel, E., Schirmer, H., Schvartzman, P., Simova, I., Sliwa, K., Stewart, S., Squire, I. B., Takeuchi, M., Altman, D., Perera, R., Triggs, C. M., Au Yeung, H., Beans Picon, G. A.
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container_end_page 348
container_issue 3
container_start_page 341
container_title European heart journal cardiovascular imaging
container_volume 15
creator Doughty, R. N.
Gardin, J. M.
Hobbs, F. D. R.
McMurray, J. J. V.
Nagueh, S. F.
Poppe, K. K.
Senior, R.
Thomas, L.
Whalley, G. A.
Aune, E.
Brown, A.
Badano, L. P.
Cameron, V.
Chadha, D. S.
Chahal, N.
Chien, K. L.
Daimon, M.
Dalen, H.
Detrano, R.
Akif Duzenli, M.
Ezekowitz, J.
de Simone, G.
Di Pasquale, P.
Fukuda, S.
Gill, P. S.
Grossman, E.
Kim, H. - K.
Kuznetsova, T.
Leung, N. K. W.
Linhart, A.
McDonagh, T. A.
McGrady, M.
Mill, J. G.
Mogelvang, R.
Muiesan, M. L.
Ng, A. C. T.
Ojji, D.
Otterstad, J. E.
Petrovic, D. J.
Prendergast, B.
Rietzschel, E.
Schirmer, H.
Schvartzman, P.
Simova, I.
Sliwa, K.
Stewart, S.
Squire, I. B.
Takeuchi, M.
Altman, D.
Perera, R.
Triggs, C. M.
Au Yeung, H.
Beans Picon, G. A.
description To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without clinical cardiovascular disease or significant cardiovascular risk factors, from multiple studies around the world. The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) collaboration was established and population-based data sets of echocardiographic measurements combined to perform an individual person data meta-analysis. Data from 43 studies were received, representing 51 222 subjects, of which 22 404 adults aged 18-80 years were without clinical cardiovascular or renal disease, hypertension or diabetes. Quantile regression or an appropriate parametric regression method will be used to derive reference values at the 5th and 95th centile of each measurement against age. This unique data set represents a large, multi-ethnic cohort of subjects resident in a wide range of countries. The resultant reference ranges will have wide applicability for normative data based on age, sex, and ethnicity.
doi_str_mv 10.1093/ehjci/jet240
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A.</creatorcontrib><creatorcontrib>Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) Collaboration</creatorcontrib><creatorcontrib>The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) Collaboration</creatorcontrib><title>A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study</title><title>European heart journal cardiovascular imaging</title><addtitle>Eur Heart J Cardiovasc Imaging</addtitle><description>To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without clinical cardiovascular disease or significant cardiovascular risk factors, from multiple studies around the world. The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) collaboration was established and population-based data sets of echocardiographic measurements combined to perform an individual person data meta-analysis. Data from 43 studies were received, representing 51 222 subjects, of which 22 404 adults aged 18-80 years were without clinical cardiovascular or renal disease, hypertension or diabetes. Quantile regression or an appropriate parametric regression method will be used to derive reference values at the 5th and 95th centile of each measurement against age. This unique data set represents a large, multi-ethnic cohort of subjects resident in a wide range of countries. 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T. ; Ojji, D. ; Otterstad, J. E. ; Petrovic, D. J. ; Prendergast, B. ; Rietzschel, E. ; Schirmer, H. ; Schvartzman, P. ; Simova, I. ; Sliwa, K. ; Stewart, S. ; Squire, I. B. ; Takeuchi, M. ; Altman, D. ; Perera, R. ; Triggs, C. M. ; Au Yeung, H. ; Beans Picon, G. 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A.</creatorcontrib><creatorcontrib>Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) Collaboration</creatorcontrib><creatorcontrib>The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) Collaboration</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European heart journal cardiovascular imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Doughty, R. N.</au><au>Gardin, J. M.</au><au>Hobbs, F. D. R.</au><au>McMurray, J. J. V.</au><au>Nagueh, S. F.</au><au>Poppe, K. K.</au><au>Senior, R.</au><au>Thomas, L.</au><au>Whalley, G. A.</au><au>Aune, E.</au><au>Brown, A.</au><au>Badano, L. P.</au><au>Cameron, V.</au><au>Chadha, D. S.</au><au>Chahal, N.</au><au>Chien, K. L.</au><au>Daimon, M.</au><au>Dalen, H.</au><au>Detrano, R.</au><au>Akif Duzenli, M.</au><au>Ezekowitz, J.</au><au>de Simone, G.</au><au>Di Pasquale, P.</au><au>Fukuda, S.</au><au>Gill, P. S.</au><au>Grossman, E.</au><au>Kim, H. - K.</au><au>Kuznetsova, T.</au><au>Leung, N. K. W.</au><au>Linhart, A.</au><au>McDonagh, T. A.</au><au>McGrady, M.</au><au>Mill, J. G.</au><au>Mogelvang, R.</au><au>Muiesan, M. L.</au><au>Ng, A. C. T.</au><au>Ojji, D.</au><au>Otterstad, J. E.</au><au>Petrovic, D. J.</au><au>Prendergast, B.</au><au>Rietzschel, E.</au><au>Schirmer, H.</au><au>Schvartzman, P.</au><au>Simova, I.</au><au>Sliwa, K.</au><au>Stewart, S.</au><au>Squire, I. B.</au><au>Takeuchi, M.</au><au>Altman, D.</au><au>Perera, R.</au><au>Triggs, C. M.</au><au>Au Yeung, H.</au><au>Beans Picon, G. A.</au><aucorp>Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) Collaboration</aucorp><aucorp>The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) Collaboration</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study</atitle><jtitle>European heart journal cardiovascular imaging</jtitle><addtitle>Eur Heart J Cardiovasc Imaging</addtitle><date>2014-03-01</date><risdate>2014</risdate><volume>15</volume><issue>3</issue><spage>341</spage><epage>348</epage><pages>341-348</pages><issn>2047-2404</issn><eissn>2047-2412</eissn><abstract>To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without clinical cardiovascular disease or significant cardiovascular risk factors, from multiple studies around the world. The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) collaboration was established and population-based data sets of echocardiographic measurements combined to perform an individual person data meta-analysis. Data from 43 studies were received, representing 51 222 subjects, of which 22 404 adults aged 18-80 years were without clinical cardiovascular or renal disease, hypertension or diabetes. Quantile regression or an appropriate parametric regression method will be used to derive reference values at the 5th and 95th centile of each measurement against age. This unique data set represents a large, multi-ethnic cohort of subjects resident in a wide range of countries. The resultant reference ranges will have wide applicability for normative data based on age, sex, and ethnicity.</abstract><cop>England</cop><pmid>24247924</pmid><doi>10.1093/ehjci/jet240</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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ispartof European heart journal cardiovascular imaging, 2014-03, Vol.15 (3), p.341-348
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2047-2412
language eng
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Alma/SFX Local Collection
subjects Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Atrial Function, Left - physiology
Cohort Studies
Echocardiography - methods
Ethnicity
Female
Heart Atria - diagnostic imaging
Heart Ventricles - diagnostic imaging
Humans
International Cooperation
Male
Middle Aged
Reference Standards
Sex Factors
Ventricular Function, Left - physiology
Young Adult
title A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study
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