Molecular HPA genotyping by microarray in Brazilian blood donors

Background Human platelet antigens (HPA) polymorphisms may cause HPA alloimmunization, platelet (PLT) refractoriness, fetomaternal alloimmune thrombocytopenia, and posttransfusion purpura. Characterized by significant racial admixture, the Brazilian population might benefit from the knowledge about...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2014-02, Vol.54 (2), p.405-411
Hauptverfasser:	Conti, Fabiana, Bertrand, Gerald, Dezan, Marcia, Costa, Thiago, Aravechia, Maria, Mota, Mariza, Castilho, Lilian, Kaplan, Cécile, Kutner, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens, Human Platelet - genetics Base Sequence Biological and medical sciences Blood & organ donations Blood Donors Blood Transfusion Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Brazil Female Gene Frequency Genotype Humans Male Medical sciences Middle Aged Molecular Sequence Data Oligonucleotide Array Sequence Analysis - methods Polymerase Chain Reaction Polymorphism, Genetic Transfusions. Complications. Transfusion reactions. Cell and gene therapy Young Adult
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