Preventive Effects of NSAIDs, NO-NSAIDs, and NSAIDs Plus Difluoromethylornithine in a Chemically Induced Urinary Bladder Cancer Model

Urinary bladder cancer prevention studies were performed with the nonsteroidal anti-inflammatory drugs (NSAID) naproxen (a standard NSAID with a good cardiovascular profile), sulindac, and their nitric oxide (NO) derivatives. In addition, the effects of the ornithine decarboxylase inhibitor, difluor...

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Veröffentlicht in:	Cancer prevention research (Philadelphia, Pa.) Pa.), 2014-02, Vol.7 (2), p.246-254
Hauptverfasser:	NICASTRO, Holly L, GRUBBS, Clinton J, LUBET, Ronald A, JULIANA, M. Margaret, BODE, Ann M, KIM, Mi-Sung, YAN LU, MING YOU, MILNE, Ginger L, BORING, Daniel, STEELE, Vernon E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Chemoprevention - methods Drug Evaluation, Preclinical Eflornithine - administration & dosage Female Medical sciences Miscellaneous Naproxen - administration & dosage Naproxen - analogs & derivatives Neoplasms, Experimental - chemically induced Neoplasms, Experimental - prevention & control Nephrology. Urinary tract diseases Nitric Oxide - administration & dosage Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Rats Rats, Inbred F344 Sulindac - administration & dosage Tumors of the urinary system Urinary Bladder Neoplasms - chemically induced Urinary Bladder Neoplasms - prevention & control Urinary tract. Prostate gland
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