Evaluation of 111In-Labeled EPep and FibPep as Tracers for Fibrin SPECT Imaging

Fibrin targeting is an attractive strategy for nuclear imaging of thrombosis, atherosclerosis and cancer. Recently, FibPep, an 111In-labeled fibrin-binding peptide, was established as a tracer for fibrin SPECT imaging and was reported to allow sensitive detection of minute thrombi in mice using SPEC...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular pharmaceutics 2013-11, Vol.10 (11), p.4309-4321
Hauptverfasser:	Starmans, Lucas W. E, van Duijnhoven, Sander M. J, Rossin, Raffaella, Berben, Monique, Aime, Silvio, Daemen, Mat J. A. P, Nicolay, Klaas, Grüll, Holger
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carotid Artery Thrombosis - diagnosis Fibrin - chemistry Humans Indium Radioisotopes Peptides - chemistry Rats Thrombosis - diagnosis Tomography, Emission-Computed, Single-Photon - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!