Purely in Silico BCS Classification: Science Based Quality Standards for the World’s Drugs

BCS classification is a vital tool in the development of both generic and innovative drug products. The purpose of this work was to provisionally classify the world’s top selling oral drugs according to the BCS, using in silico methods. Three different in silico methods were examined: the well-estab...

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Veröffentlicht in:	Molecular pharmaceutics 2013-11, Vol.10 (11), p.4378-4390
Hauptverfasser:	Dahan, Arik, Wolk, Omri, Kim, Young Hoon, Ramachandran, Chandrasekharan, Crippen, Gordon M, Takagi, Toshihide, Bermejo, Marival, Amidon, Gordon L
Format:	Artikel
Sprache:	eng
Schlagworte:	Israel Japan Metoprolol - chemistry Republic of Korea Solubility Spain Thermodynamics United Kingdom United States
Online-Zugang:	Volltext
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