Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application
•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted...
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Veröffentlicht in: | Food chemistry 2014-06, Vol.153, p.361-370 |
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description | •Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings.
Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance. |
doi_str_mv | 10.1016/j.foodchem.2013.12.067 |
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Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.</description><identifier>ISSN: 0308-8146</identifier><identifier>EISSN: 1873-7072</identifier><identifier>DOI: 10.1016/j.foodchem.2013.12.067</identifier><identifier>PMID: 24491741</identifier><identifier>CODEN: FOCHDJ</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>beta-Cyclodextrins - chemistry ; Biological and medical sciences ; Co-precipitation ; Curcumin ; Curcumin - chemistry ; Cyclodextrin ; Food toxicology ; Hydrogen-Ion Concentration ; Medical sciences ; Molecular inclusion ; Natural colourant ; Polymers - chemistry ; Solubility ; Spectroscopic techniques ; Spectroscopy, Fourier Transform Infrared ; Spectrum Analysis ; Spectrum Analysis, Raman ; Toxicology ; X-Ray Diffraction</subject><ispartof>Food chemistry, 2014-06, Vol.153, p.361-370</ispartof><rights>2013 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</citedby><cites>FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0308814613019353$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28318974$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24491741$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mangolim, Camila Sampaio</creatorcontrib><creatorcontrib>Moriwaki, Cristiane</creatorcontrib><creatorcontrib>Nogueira, Ana Claudia</creatorcontrib><creatorcontrib>Sato, Francielle</creatorcontrib><creatorcontrib>Baesso, Mauro Luciano</creatorcontrib><creatorcontrib>Neto, Antônio Medina</creatorcontrib><creatorcontrib>Matioli, Graciette</creatorcontrib><title>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</title><title>Food chemistry</title><addtitle>Food Chem</addtitle><description>•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings.
Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.</description><subject>beta-Cyclodextrins - chemistry</subject><subject>Biological and medical sciences</subject><subject>Co-precipitation</subject><subject>Curcumin</subject><subject>Curcumin - chemistry</subject><subject>Cyclodextrin</subject><subject>Food toxicology</subject><subject>Hydrogen-Ion Concentration</subject><subject>Medical sciences</subject><subject>Molecular inclusion</subject><subject>Natural colourant</subject><subject>Polymers - chemistry</subject><subject>Solubility</subject><subject>Spectroscopic techniques</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Spectrum Analysis</subject><subject>Spectrum Analysis, Raman</subject><subject>Toxicology</subject><subject>X-Ray Diffraction</subject><issn>0308-8146</issn><issn>1873-7072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2O1DAQhS0EYpqBK4y8QWLRCXb-7GbFqMXASCMhDYPEzqqUHbVbSRzsBE123IGLIA7CITgJDt0NS1Zlyd97Lr9HyAVnKWe8erlPG-c07kyXZoznKc9SVokHZMWlyBPBRPaQrFjOZCJ5UZ2RJyHsGWORlY_JWVYUGy4KviLft5PHqbP9r6_ffv5IcMbWaXM_ettT22M7Bet6iq4bWnP_in4YobatHec1Da6dTmfcgQccjbcBxkVQz_TqLrm-XS_jFjro1_RT4mGm2jbNwi4U9JoOOzc6QDeF0SINg8HRu4BuiLbL_fJNCsPQWvxj_ZQ8aqAN5tlxnpOPV2_utu-Sm_dvr7eXNwkWRTUmJuc1MMGlriHnuswMokYt81JLziArsQahTVNFrMyqumxQAMrCCF40ArL8nLw4-A7efZ5MGFVnA5q2hd7EZRUvNhueCSlZRKsDinHz4E2jBm878LPiTC1tqb06taWWthTPVGwrCi-Ob0x1Z_Rf2ameCDw_AhAQ2hhcjzb842TO5UYUkXt94ExM5Is1XgW0pkejrY-BKu3s_3b5DYQ6vRc</recordid><startdate>20140615</startdate><enddate>20140615</enddate><creator>Mangolim, Camila Sampaio</creator><creator>Moriwaki, Cristiane</creator><creator>Nogueira, Ana Claudia</creator><creator>Sato, Francielle</creator><creator>Baesso, Mauro Luciano</creator><creator>Neto, Antônio Medina</creator><creator>Matioli, Graciette</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140615</creationdate><title>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</title><author>Mangolim, Camila Sampaio ; Moriwaki, Cristiane ; Nogueira, Ana Claudia ; Sato, Francielle ; Baesso, Mauro Luciano ; Neto, Antônio Medina ; Matioli, Graciette</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>beta-Cyclodextrins - chemistry</topic><topic>Biological and medical sciences</topic><topic>Co-precipitation</topic><topic>Curcumin</topic><topic>Curcumin - chemistry</topic><topic>Cyclodextrin</topic><topic>Food toxicology</topic><topic>Hydrogen-Ion Concentration</topic><topic>Medical sciences</topic><topic>Molecular inclusion</topic><topic>Natural colourant</topic><topic>Polymers - chemistry</topic><topic>Solubility</topic><topic>Spectroscopic techniques</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Spectrum Analysis</topic><topic>Spectrum Analysis, Raman</topic><topic>Toxicology</topic><topic>X-Ray Diffraction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mangolim, Camila Sampaio</creatorcontrib><creatorcontrib>Moriwaki, Cristiane</creatorcontrib><creatorcontrib>Nogueira, Ana Claudia</creatorcontrib><creatorcontrib>Sato, Francielle</creatorcontrib><creatorcontrib>Baesso, Mauro Luciano</creatorcontrib><creatorcontrib>Neto, Antônio Medina</creatorcontrib><creatorcontrib>Matioli, Graciette</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mangolim, Camila Sampaio</au><au>Moriwaki, Cristiane</au><au>Nogueira, Ana Claudia</au><au>Sato, Francielle</au><au>Baesso, Mauro Luciano</au><au>Neto, Antônio Medina</au><au>Matioli, Graciette</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</atitle><jtitle>Food chemistry</jtitle><addtitle>Food Chem</addtitle><date>2014-06-15</date><risdate>2014</risdate><volume>153</volume><spage>361</spage><epage>370</epage><pages>361-370</pages><issn>0308-8146</issn><eissn>1873-7072</eissn><coden>FOCHDJ</coden><abstract>•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings.
Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>24491741</pmid><doi>10.1016/j.foodchem.2013.12.067</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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subjects | beta-Cyclodextrins - chemistry Biological and medical sciences Co-precipitation Curcumin Curcumin - chemistry Cyclodextrin Food toxicology Hydrogen-Ion Concentration Medical sciences Molecular inclusion Natural colourant Polymers - chemistry Solubility Spectroscopic techniques Spectroscopy, Fourier Transform Infrared Spectrum Analysis Spectrum Analysis, Raman Toxicology X-Ray Diffraction |
title | Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application |
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