Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application

•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Food chemistry 2014-06, Vol.153, p.361-370
Hauptverfasser: Mangolim, Camila Sampaio, Moriwaki, Cristiane, Nogueira, Ana Claudia, Sato, Francielle, Baesso, Mauro Luciano, Neto, Antônio Medina, Matioli, Graciette
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 370
container_issue
container_start_page 361
container_title Food chemistry
container_volume 153
creator Mangolim, Camila Sampaio
Moriwaki, Cristiane
Nogueira, Ana Claudia
Sato, Francielle
Baesso, Mauro Luciano
Neto, Antônio Medina
Matioli, Graciette
description •Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings. Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.
doi_str_mv 10.1016/j.foodchem.2013.12.067
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1499127880</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0308814613019353</els_id><sourcerecordid>1499127880</sourcerecordid><originalsourceid>FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</originalsourceid><addsrcrecordid>eNqFkU2O1DAQhS0EYpqBK4y8QWLRCXb-7GbFqMXASCMhDYPEzqqUHbVbSRzsBE123IGLIA7CITgJDt0NS1Zlyd97Lr9HyAVnKWe8erlPG-c07kyXZoznKc9SVokHZMWlyBPBRPaQrFjOZCJ5UZ2RJyHsGWORlY_JWVYUGy4KviLft5PHqbP9r6_ffv5IcMbWaXM_ettT22M7Bet6iq4bWnP_in4YobatHec1Da6dTmfcgQccjbcBxkVQz_TqLrm-XS_jFjro1_RT4mGm2jbNwi4U9JoOOzc6QDeF0SINg8HRu4BuiLbL_fJNCsPQWvxj_ZQ8aqAN5tlxnpOPV2_utu-Sm_dvr7eXNwkWRTUmJuc1MMGlriHnuswMokYt81JLziArsQahTVNFrMyqumxQAMrCCF40ArL8nLw4-A7efZ5MGFVnA5q2hd7EZRUvNhueCSlZRKsDinHz4E2jBm878LPiTC1tqb06taWWthTPVGwrCi-Ob0x1Z_Rf2ameCDw_AhAQ2hhcjzb842TO5UYUkXt94ExM5Is1XgW0pkejrY-BKu3s_3b5DYQ6vRc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1499127880</pqid></control><display><type>article</type><title>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Mangolim, Camila Sampaio ; Moriwaki, Cristiane ; Nogueira, Ana Claudia ; Sato, Francielle ; Baesso, Mauro Luciano ; Neto, Antônio Medina ; Matioli, Graciette</creator><creatorcontrib>Mangolim, Camila Sampaio ; Moriwaki, Cristiane ; Nogueira, Ana Claudia ; Sato, Francielle ; Baesso, Mauro Luciano ; Neto, Antônio Medina ; Matioli, Graciette</creatorcontrib><description>•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings. Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.</description><identifier>ISSN: 0308-8146</identifier><identifier>EISSN: 1873-7072</identifier><identifier>DOI: 10.1016/j.foodchem.2013.12.067</identifier><identifier>PMID: 24491741</identifier><identifier>CODEN: FOCHDJ</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>beta-Cyclodextrins - chemistry ; Biological and medical sciences ; Co-precipitation ; Curcumin ; Curcumin - chemistry ; Cyclodextrin ; Food toxicology ; Hydrogen-Ion Concentration ; Medical sciences ; Molecular inclusion ; Natural colourant ; Polymers - chemistry ; Solubility ; Spectroscopic techniques ; Spectroscopy, Fourier Transform Infrared ; Spectrum Analysis ; Spectrum Analysis, Raman ; Toxicology ; X-Ray Diffraction</subject><ispartof>Food chemistry, 2014-06, Vol.153, p.361-370</ispartof><rights>2013 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</citedby><cites>FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0308814613019353$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=28318974$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24491741$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mangolim, Camila Sampaio</creatorcontrib><creatorcontrib>Moriwaki, Cristiane</creatorcontrib><creatorcontrib>Nogueira, Ana Claudia</creatorcontrib><creatorcontrib>Sato, Francielle</creatorcontrib><creatorcontrib>Baesso, Mauro Luciano</creatorcontrib><creatorcontrib>Neto, Antônio Medina</creatorcontrib><creatorcontrib>Matioli, Graciette</creatorcontrib><title>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</title><title>Food chemistry</title><addtitle>Food Chem</addtitle><description>•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings. Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.</description><subject>beta-Cyclodextrins - chemistry</subject><subject>Biological and medical sciences</subject><subject>Co-precipitation</subject><subject>Curcumin</subject><subject>Curcumin - chemistry</subject><subject>Cyclodextrin</subject><subject>Food toxicology</subject><subject>Hydrogen-Ion Concentration</subject><subject>Medical sciences</subject><subject>Molecular inclusion</subject><subject>Natural colourant</subject><subject>Polymers - chemistry</subject><subject>Solubility</subject><subject>Spectroscopic techniques</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Spectrum Analysis</subject><subject>Spectrum Analysis, Raman</subject><subject>Toxicology</subject><subject>X-Ray Diffraction</subject><issn>0308-8146</issn><issn>1873-7072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2O1DAQhS0EYpqBK4y8QWLRCXb-7GbFqMXASCMhDYPEzqqUHbVbSRzsBE123IGLIA7CITgJDt0NS1Zlyd97Lr9HyAVnKWe8erlPG-c07kyXZoznKc9SVokHZMWlyBPBRPaQrFjOZCJ5UZ2RJyHsGWORlY_JWVYUGy4KviLft5PHqbP9r6_ffv5IcMbWaXM_ettT22M7Bet6iq4bWnP_in4YobatHec1Da6dTmfcgQccjbcBxkVQz_TqLrm-XS_jFjro1_RT4mGm2jbNwi4U9JoOOzc6QDeF0SINg8HRu4BuiLbL_fJNCsPQWvxj_ZQ8aqAN5tlxnpOPV2_utu-Sm_dvr7eXNwkWRTUmJuc1MMGlriHnuswMokYt81JLziArsQahTVNFrMyqumxQAMrCCF40ArL8nLw4-A7efZ5MGFVnA5q2hd7EZRUvNhueCSlZRKsDinHz4E2jBm878LPiTC1tqb06taWWthTPVGwrCi-Ob0x1Z_Rf2ameCDw_AhAQ2hhcjzb842TO5UYUkXt94ExM5Is1XgW0pkejrY-BKu3s_3b5DYQ6vRc</recordid><startdate>20140615</startdate><enddate>20140615</enddate><creator>Mangolim, Camila Sampaio</creator><creator>Moriwaki, Cristiane</creator><creator>Nogueira, Ana Claudia</creator><creator>Sato, Francielle</creator><creator>Baesso, Mauro Luciano</creator><creator>Neto, Antônio Medina</creator><creator>Matioli, Graciette</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140615</creationdate><title>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</title><author>Mangolim, Camila Sampaio ; Moriwaki, Cristiane ; Nogueira, Ana Claudia ; Sato, Francielle ; Baesso, Mauro Luciano ; Neto, Antônio Medina ; Matioli, Graciette</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-e31ba0718dba31d52eccdcd835d810a25cba7def61ba526b5fc7ac84e714f7a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>beta-Cyclodextrins - chemistry</topic><topic>Biological and medical sciences</topic><topic>Co-precipitation</topic><topic>Curcumin</topic><topic>Curcumin - chemistry</topic><topic>Cyclodextrin</topic><topic>Food toxicology</topic><topic>Hydrogen-Ion Concentration</topic><topic>Medical sciences</topic><topic>Molecular inclusion</topic><topic>Natural colourant</topic><topic>Polymers - chemistry</topic><topic>Solubility</topic><topic>Spectroscopic techniques</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Spectrum Analysis</topic><topic>Spectrum Analysis, Raman</topic><topic>Toxicology</topic><topic>X-Ray Diffraction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mangolim, Camila Sampaio</creatorcontrib><creatorcontrib>Moriwaki, Cristiane</creatorcontrib><creatorcontrib>Nogueira, Ana Claudia</creatorcontrib><creatorcontrib>Sato, Francielle</creatorcontrib><creatorcontrib>Baesso, Mauro Luciano</creatorcontrib><creatorcontrib>Neto, Antônio Medina</creatorcontrib><creatorcontrib>Matioli, Graciette</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mangolim, Camila Sampaio</au><au>Moriwaki, Cristiane</au><au>Nogueira, Ana Claudia</au><au>Sato, Francielle</au><au>Baesso, Mauro Luciano</au><au>Neto, Antônio Medina</au><au>Matioli, Graciette</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application</atitle><jtitle>Food chemistry</jtitle><addtitle>Food Chem</addtitle><date>2014-06-15</date><risdate>2014</risdate><volume>153</volume><spage>361</spage><epage>370</epage><pages>361-370</pages><issn>0308-8146</issn><eissn>1873-7072</eissn><coden>FOCHDJ</coden><abstract>•Curcumin–β-CD complex using co-precipitation enhanced its solubility 31-fold.•Curcumin–β-CD complex exhibited higher sunlight, pH, storage and heating stability.•XRD and the spectroscopic techniques produced important evidences of complexation.•The use of the complex in vanilla ice creams resulted in potential savings. Curcumin was complexed with β-CD using co-precipitation, freeze-drying and solvent evaporation methods. Co-precipitation enabled complex formation, as indicated by the FT-IR and FT-Raman techniques via the shifts in the peaks that were assigned to the aromatic rings of curcumin. In addition, photoacoustic spectroscopy and X-ray diffraction, with the disappearance of the band related to aromatic rings, by Gaussian fitting, and modifications in the spectral lines, respectively, also suggested complex formation. The possible complexation had an efficiency of 74% and increased the solubility of the pure colourant 31-fold. Curcumin–β-CD complex exhibited a sunlight stability 18% higher than the pure colourant. This material was stable to pH variations and storage at −15 and 4°C. With an isothermal heating at 100 and 150°C for 2h, the material exhibited a colour retention of approximately 99%. The application of curcumin–β-CD complex in vanilla ice creams intensified the colour of the products and produced a great sensorial acceptance.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>24491741</pmid><doi>10.1016/j.foodchem.2013.12.067</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0308-8146
ispartof Food chemistry, 2014-06, Vol.153, p.361-370
issn 0308-8146
1873-7072
language eng
recordid cdi_proquest_miscellaneous_1499127880
source MEDLINE; Elsevier ScienceDirect Journals
subjects beta-Cyclodextrins - chemistry
Biological and medical sciences
Co-precipitation
Curcumin
Curcumin - chemistry
Cyclodextrin
Food toxicology
Hydrogen-Ion Concentration
Medical sciences
Molecular inclusion
Natural colourant
Polymers - chemistry
Solubility
Spectroscopic techniques
Spectroscopy, Fourier Transform Infrared
Spectrum Analysis
Spectrum Analysis, Raman
Toxicology
X-Ray Diffraction
title Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T03%3A49%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Curcumin%E2%80%93%CE%B2-cyclodextrin%20inclusion%20complex:%20Stability,%20solubility,%20characterisation%20by%20FT-IR,%20FT-Raman,%20X-ray%20diffraction%20and%20photoacoustic%20spectroscopy,%20and%20food%20application&rft.jtitle=Food%20chemistry&rft.au=Mangolim,%20Camila%20Sampaio&rft.date=2014-06-15&rft.volume=153&rft.spage=361&rft.epage=370&rft.pages=361-370&rft.issn=0308-8146&rft.eissn=1873-7072&rft.coden=FOCHDJ&rft_id=info:doi/10.1016/j.foodchem.2013.12.067&rft_dat=%3Cproquest_cross%3E1499127880%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1499127880&rft_id=info:pmid/24491741&rft_els_id=S0308814613019353&rfr_iscdi=true