Formation of Substituted Tetrahydropyrans through Oxetane Ring Opening: Application to the Synthesis of C1–C17 Fragment of Salinomycin

The stereoselective synthesis of C1–C17 fragment of salinomycin is achieved. The strategy employs a desymmetrization approach and utilizes an intramolecular oxetane opening reaction with O-nucleophile to result in the tetrahydropyran skeleton as the key step.

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2014-02, Vol.16 (3), p.836-839
Hauptverfasser:	Yadav, J. S, Singh, Vinay K, Srihari, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Ethers, Cyclic - chemistry Molecular Structure Pyrans - chemistry Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!